The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

Hibaoui, Lahbib; Massik, Abdelhamid; Lebbar, Zina; Yahyaoui, Ghita; Mahmoud, Mustapha; Bougnouch, Laila; Hamass, Naoual; Chbani, Laïla; Bennani, Bahia; Berrahou, Mohamed Amine; Idriss, Mounia Lakhdar; Hida, M.

doi:10.18502/ijm.v14i5.10960

Cited by 2 publications

(2 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sensitivity and specificity are essential indicators of test accuracy and allow healthcare providers to determine the appropriateness of the diagnostic tool aiding in decision-making and improving healthcare for patients [ 23 ]. It is critical to use at least two diagnostic tests with high sensitivity and specificity based on the clinical situation to achieve an accurate diagnosis of the pathogen [ 24 , 25 ]. Therefore, the sensitivity, specificity, and limitations of the H. pylori detection test, which plays a critical role in the accurate diagnosis and assessment of the presence of the bacteria, are presented in Table 2 .…”

Section: Methods For Detecting H Pylorimentioning

confidence: 99%

Diagnostic Methods for <i>Helicobacter pylori</i>

Costa,

das Graças Carvalho,

La Guárdia Custódio Pereira

et al. 2024

Med Princ Pract

View full text Add to dashboard Cite

H. pylori infection is a significant global health concern. It cannot be diagnosed based solely on the patient's medical history and symptoms, and laboratory and imaging tests are often required to confirm the diagnosis. Both non-invasive and invasive methods are available for diagnosing H. pylori infection, including conventional and advanced detection techniques. It is not uncommon for patients to present with false-negative results due to the use of inadequate investigation methodologies, which prevents the adoption of appropriate clinical management. Thus, an analysis of the literature regarding the methods of diagnosis of H. pylori, with its advantages and disadvantages, is necessary. Publications in specialized scientific journals will undoubtedly contribute to facilitating access by professionals interested in the topic providing greater knowledge and potentially clinically useful guidance. In this review, the authors have sought to analyze and summarize the invasive and non-invasive methods, their applications, limitations, and the conditions that affect the sensitivity of the tests used for diagnosing H. pylori, an essential step for the successful treatment of this infection. It is essential to treat all patients infected with H. pylori. This represents a significant change in the approach, as previously treatment was recommended only for patients showing symptoms of infection. Therefore, it is crucial to understand the limitations of traditional diagnostic methods and help raise awareness among healthcare professionals about the latest advances in diagnosing this important bacterium.

show abstract

Section: Methods For Detecting H Pylorimentioning

confidence: 99%

Diagnostic Methods for <i>Helicobacter pylori</i>

Costa,

das Graças Carvalho,

La Guárdia Custódio Pereira

et al. 2024

Med Princ Pract

View full text Add to dashboard Cite

show abstract

“…Among the various diagnostic tests for the detection of H. pylori infection, the rapid urease test (RUT) is a comparatively precise and rapid method and is suggested as a first-line diagnostic method [14][15][16][17][18][19]. As a "test and treat" approach was recommended for H. pylori-infected patients in the Maastricht V consensus [7], the rapidity and accuracy of the diagnostic test for H. pylori are valuable.…”

Section: Introductionmentioning

confidence: 99%

Prospective Evaluation of a New Liquid-Type Rapid Urease Test Kit for Diagnosis of Helicobacter pylori

Kim,

Joo

et al. 2024

Diagnostics

View full text Add to dashboard Cite

Background/Aims: Rapid and accurate diagnostic tools are essential for the timely recognition of Helicobacter pylori (H. pylori) in clinical practice. The rapid urease test (RUT) is a comparatively accurate and time-saving method recommended as a first-line diagnostic test. The primary objective of conducting the RUT is to obtain rapid results, thus enabling the initiation of an eradication therapy based on clarithromycin resistance testing. This study aimed to assess the reaction time and accuracy of a new liquid-type RUT. Method: In this prospective study, consecutive dyspeptic or check-up patients referred to our clinic for endoscopy were assessed to evaluate the rapidity and accuracy of a novel liquid-type RUT (Helicotest®, WON Medical, Bucheon, Republic of Korea) compared with another commercial RUT kit (HP kit, Chong Kun Dang, Seoul, Republic of Korea) and a real-time quantitative PCR-based assay (Seeplex® H.pylori-ClaR Detection, Seegene, Republic of Korea). RUTs were analyzed at 10 min, 30 min, 60 min, and 120 min. Results: Among the 177 enrolled patients, 38.6% were infected with H. pylori. The positivity rates of the liquid-type RUT were 26.1, 35.8, 39.2%, and 41.5% at 10, 30, 60, and 120 min, respectively. When compared with the HP kit test, the time needed to confirm positivity was significantly reduced by 28.6 min (95% CI, 16.60–39.73, p < 0.0001). Helicotest® had a greater accuracy (96.02 ± 1.47), sensitivity (98.53 ± 1.46) and NPV (99.03 ± 0.97) compared to the HP kit. Conclusions: Compared to the commonly used RUT, the new liquid-type RUT presented faster and reliable results. Such findings could improve H. pylori treatment outcomes, particularly in outpatient clinical settings.

show abstract

The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

Cited by 2 publications

References 46 publications

Diagnostic Methods for <i>Helicobacter pylori</i>

Diagnostic Methods for <i>Helicobacter pylori</i>

Prospective Evaluation of a New Liquid-Type Rapid Urease Test Kit for Diagnosis of Helicobacter pylori

Contact Info

Product

Resources

About