The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

Kotov, Roman; Krueger, Robert F.; Watson, David; Achenbach, Thomas M.; Althoff, Robert R.; Bagby, Michael; Brown, Timothy M.; Docherty, Anna R.; Miller, Josh; Simms, Leonard J.; South, Susan C.; Tackett, Jennifer L.

doi:10.31234/osf.io/zaadn

Cited by 502 publications

(1,009 citation statements)

References 97 publications

(115 reference statements)

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“…A Hierarchical Taxonomy of Psychopathology (HiTOP) has subsequently been established to integrate the vast body of research that has tested factor analytic models of dimensional spectra into a single descriptive model of the meta-structure that includes 11 of the 19 DSM chapters, and six spectra, including internalizing and externalizing (Kotov et al, under review). …”

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

“…For example, spectra can account for the roles of genetic and environmental risk and protective factors, predict disorder onset, course and treatment response, and predict adaptive functioning (Eaton et al, 2015a; Kessler et al, 2011; Kim & Eaton, in press; Krueger & Eaton, 2015; Lahey, Zald, Hakes, Krueger & Rathouz, 2014; Rodriguez-Seijas, Stohl, Hasin & Eaton, 2015). These spectra also frame the development of psychopathology across the lifespan, and can act as a bridge between multiple streams of research (e.g., nosological research, developmental psychopathology research, neuropsychology research, and clinical practice; Forbes et al, 2016; Kotov et al, under review). As such, the empirically derived spectra of psychopathology offer ideal phenotypes to frame future research.…”

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

“…Sexual dysfunctions have been tentatively included in HiTOP as part of the internalizing spectrum based on work by Forbes and colleagues on self-report data from convenience samples (Forbes, Baillie & Schniering, 2015a, 2015b, 2016; Forbes & Schniering, 2013), which are reviewed in detail in Part 3. However, empirical evidence for the inclusion of sexual dysfunctions in HiTOP is at the lowest standard (i.e., emerging evidence with scant validation; Kotov et al, under review), and they are at risk of being left behind.…”

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

“…While the HiTOP model is based on the results of studies that have empirically analyzed the factor structure of the descriptive features of psychopathology (Kotov et al, under review), an earlier framework outlined a substantive approach with which to build hypotheses about the classification of mental disorders into spectra in the lead-up to the DSM-5 (Andrews et al, 2009). The APA Diagnostic Spectra Study Group of the DSM-5 suggested eleven criteria to support the validity of a spectrum: (1) comorbidity, (2) abnormalities of cognitive/emotional processing, (3) temperamental antecedents, (4) treatment response, (5) symptoms, (6) neural substrates, (7) biomarkers, (8) illness course, (9) genetic risk factors, (10) familial risk factors, and (11) environmental risk factors.…”

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

“…There is currently evidence that a variety of DSM-5 disorders may be manifestations of the internalizing spectrum, including: depressive and anxiety disorders, obsessive-compulsive and related disorders, trauma and stressor-related disorders, bipolar and related disorders, somatic symptom disorders, and feeding and eating disorders (Kotov et al, under review). Many of these disorders share traits like repetitive negative thinking, perfectionism, and emotion avoidance (Barlow et al, 2010; Ehring & Watkins, 2008; Mills et al, 2016).…”

Section: Part 2: Evidence That Supports the Formation Of The Hypothesmentioning

confidence: 99%

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A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology

Forbes

Baillie

Eaton

et al. 2017

The Journal of Sex Research

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Sexual dysfunctions commonly co-occur with various depressive and anxiety disorders. An emerging framework for understanding the classification of mental disorders suggests that such comorbidity is a manifestation of underlying dimensions of psychopathology (or “spectra”). In this review, we synthesize the evidence that sexual dysfunctions should be included in the empirical taxonomy of psychopathology as part of the internalizing spectrum, which accounts for comorbidity among the depressive and anxiety disorders. The review has four parts. Part 1 summarizes the empirical basis and utility of the empirical taxonomy of psychopathology. Part 2 reviews the prima facie evidence for the hypothesis that sexual dysfunctions are part of the internalizing spectrum (i.e., high rates of comorbidity; shared cognitive, affective, and temperament characteristics; common neural substrates and biomarkers; shared course and treatment response; and the lack of causal relationships between them). Part 3 critically analyzes and integrates the results of the eight studies that have addressed this hypothesis. Finally, Part 4 examines the implications of reconceptualizing sexual dysfunctions as part of the internalizing spectrum, and explores avenues for future research.

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Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

Section: Part 1: Current Thinking About the Structure Of Psychopathologymentioning

confidence: 99%

Section: Part 2: Evidence That Supports the Formation Of The Hypothesmentioning

confidence: 99%

See 3 more Smart Citations

A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology

Forbes

Baillie

Eaton

et al. 2017

The Journal of Sex Research

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Traumatic brain injury and adverse psychological effects: Examining a potential pathway to aggressive offending

Silver

Nedelec

2020

Aggressive Behavior

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Contemporary scholarship has demonstrated an association between traumatic brain injury (TBI) during adolescence and aggressive offending. Research, however, has yet to identify any mechanisms linking TBI to subsequent aggressive offending. Consequently, the current study hypothesized that adverse psychological effects is one such pathway. The current study used the Pathways to Desistance data set (n = 416) to examine the pathway of TBI to aggressive offending through adverse psychological effects. The findings of the structural equation model supported the hypothesized association. Specifically, increased exposure to TBI was indirectly associated with aggressive offending through adverse psychological effects. An additional supplemental analysis illustrated that a direct link between TBI and aggressive offending did not exist for the analytical sample. The findings suggested that the neurological disruptions commonly associated with TBI could result in direct increases in negative psychological outcomes and indirect increases in subsequent negative behavioral outcomes.

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Internalizing and externalizing symptoms and aggression and violence in men and women

Mendez

Bozzay²,

Verona

2021

Aggressive Behavior

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Literature linking aggressive behavior across internalizing and externalizing disorders support the co‐occurrence of aggression and various mental health diagnoses. However, research has yet to examine relationships between aggression and dimensional psychopathology models that cut across diagnostic boundaries (e.g., internalizing, externalizing composites) and capture shared liability across common disorders. The role of gender has also been largely ignored in prior work, despite evidence that men and women manifest psychopathology differently. The present study examined cross‐sectional and longitudinal relationships between psychopathology composites (i.e., Internalizing, Externalizing) and different manifestations of physical aggression (i.e., aggressive traits, general violence, physical intimate partner violence, and self‐directed aggression), as well as moderation by gender. Internalizing (INT) and Externalizing (EXT) lifetime symptoms and various physically aggressive behaviors were assessed at baseline and at 6 months and 1 year follow up in a sample of 319 adults with violence and/or substance use histories. Cross‐sectional results showed that INT was associated with all forms of aggression, and women showed stronger relationships between INT and both physical intimate partner violence (IPV) and self‐directed aggression. EXT was specifically linked to general violence, and a stronger relationship between EXT and self‐directed aggression emerged in men compared to women. Longitudinal relationships were mostly small and nonsignificant. Results support the co‐occurrence of aggression with distinct forms of psychopathology, as well as gender‐dependent relationships, but do not support the predictive validity of symptom composites in aggression risk. Findings implicate the need for aggression interventions tailored within gender.

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The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

Cited by 502 publications

References 97 publications

A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology

A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology

Traumatic brain injury and adverse psychological effects: Examining a potential pathway to aggressive offending

Internalizing and externalizing symptoms and aggression and violence in men and women

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