The heterogeneous course of OCD – A scoping review on the variety of definitions

Kühne, Franziska; Ay, Destina Sevde; Marschner, Linda; Weck, Florian

doi:10.1016/j.psychres.2020.112821

Cited by 14 publications

(6 citation statements)

References 35 publications

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“…Effective short-term pharmacological and psychotherapeutic treatments for adult patients with OCD are well-established (Skapinakis et al, 2016;Guzick et al, 2018). However, a notable number of individuals experience residual OCD symptoms, which have been shown to follow the long-term rates of remission and relapse (Skoog and Skoog, 1999;Eisen et al, 2013;Kuehne et al, 2020).…”

Section: Introduction Obsessive-compulsive Disordermentioning

confidence: 99%

Associations of Autism Traits With Obsessive Compulsive Symptoms and Well-Being in Patients With Obsessive Compulsive Disorder: A Cross-Sectional Study

et al. 2021

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The aim of this study is to examine the association of autism traits with long-term obsessive compulsive disorder (OCD) symptoms and well-being levels in patient with OCD. Participants comprised 18 outpatients from a tertiary hospital and 100 adults who were registered in a large Japanese internet marketing research company and met OCD criteria by the Mini-International Neuropsychiatric Interview and were between the ages of 20 and 65 years. Clinical characteristics, autism trait assessed using the Autism Spectrum Quotient (AQ), OCD symptoms assessed using Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), and well-being assessed using the Flourishing Scale were assessed. Multiple regression analyses showed that a greater total score of AQ, a greater subscale score “imagination” was associated with a greater score of Y-BOCS. Greater total score of AQ, a greater subscale score “social skill,” and “imagination” were associated with lower well-being score. Autism traits, especially lack of imagination, were associated with more severe OCD symptoms. Further, autism traits, especially social skill problems and lack of imagination, were associated with lower levels of well-being. Assessment of autism traits before treatment and a strategy designed for OCD patients with autism traits may be warranted.

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Section: Introduction Obsessive-compulsive Disordermentioning

confidence: 99%

Associations of Autism Traits With Obsessive Compulsive Symptoms and Well-Being in Patients With Obsessive Compulsive Disorder: A Cross-Sectional Study

et al. 2021

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“…There were five key limitations that warrant discussion. First, random-effect models were used for all meta-analyses because OCRDs are highly heterogenous mental health conditions and as such we expected that heterogeneity would be high (Kühne et al, 2020) and because there are other sources of heterogeneity that may remain unexplained. However, it should be noted that the heterogeneity for BDD and TTM was low, which can be explained by the small sample sizes in these comparison groups (von Hippel, 2015).…”

Section: Discussionmentioning

confidence: 99%

Mindfulness interventions for obsessive–compulsive and related disorders: A systematic review and meta-analysis of randomized controlled trials.

Pseftogianni¹,

Panagioti²,

Birtwell³

et al. 2023

Clinical Psychology: Science and Practice

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Mindfulness interventions (MIs) emphasize living in the present moment without being judgmental of one's feelings and sensations. We aimed to evaluate the effectiveness of MIs, including both mindfulness-based and mindfulness-informed interventions, in reducing overall obsessive-compulsive and related disorders (OCRDs) severity and comorbid depression at post-treatment and in the long-term. The potential contribution of methodological variables moderating the effectiveness of MIs was examined. Five databases (Medline, PsychInfo, Embase, Web of Science, Cochrane Register of Controlled Trials) were searched until May 2022. The pooled standardized mean difference was calculated using random effect models. Twenty-six studies with 1,281 participants were included. We found moderate to large reductions in overall OCRDs severity in favor of MIs at post-treatment (SMD ranging between −0.62 and −1.52, 95% CI: −2.02 to −0.22). MIs were associated with small reductions of depression in people with OCD (SMD = −0.30 and −0.52, 95% CI: −0.68 to −0.09) and obsessions (SMD = −0.32, 95% CI: −0.65 to −0.01) at post-treatment but these effects were not sustained at follow-up. Meta-regression analyses showed that Acceptance and Commitment Therapy (ACT) and Mindfulness-Based Cognitive Therapy (MBCT) appeared to be effective in treating OCD and/or depressive symptoms in these patients. Lower income countries contributed larger effect sizes. Our findings provide first evidence of the effectiveness of MIs in reducing OCRDs severity which require further exploration from high quality RCT studies with embedded qualitative research. Public Health Significance StatementExposure-based psychological interventions are the gold standard for treating obsessive-compulsive and related disorders. However, dropout rates remain one of their biggest limitations. This meta-analytic review showed that mindfulness interventions, which can be both acceptable and have low attrition rates, can be effective in treating these disorders.

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“…Given that OCD is a heterogeneous disorder and dimensional in nature ( Kühne et al, 2020 ), some individuals with OCD only have symptoms corresponding to one dimension of OCD while others have symptoms across multiple dimensions ( Cromer et al, 2007 ). Research on OCD dimension stability is scarce.…”

Section: The Perceived Impact Of Covid-19 On Ocd Symptomologymentioning

confidence: 99%

The perceived long-term impact of COVID-19 on OCD symptomology

Dennis

McGlinchey

Wheaton

2023

Journal of Obsessive-Compulsive and Related Disorders

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The heterogeneous course of OCD – A scoping review on the variety of definitions

Cited by 14 publications

References 35 publications

Associations of Autism Traits With Obsessive Compulsive Symptoms and Well-Being in Patients With Obsessive Compulsive Disorder: A Cross-Sectional Study

Associations of Autism Traits With Obsessive Compulsive Symptoms and Well-Being in Patients With Obsessive Compulsive Disorder: A Cross-Sectional Study

Mindfulness interventions for obsessive–compulsive and related disorders: A systematic review and meta-analysis of randomized controlled trials.

The perceived long-term impact of COVID-19 on OCD symptomology

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