The heritability of attained growth in the human face

Hunter, W. Stuart; Balbach, Daniel R.; Lamphiear, Donald E.

doi:10.1016/0002-9416(70)90066-7

Cited by 50 publications

(25 citation statements)

References 8 publications

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“…The simplistic assumption, viz. 'the son will look like the father and the daughter will look like the mother after the growth is over' [6][7][8] was found to be unreliable from the correlations established in our study. It may apply to some features but may be totally wrong for other features.…”

Section: Possibility Of Forecasting Adult Formcontrasting

confidence: 71%

Facial Soft Tissue Similarity between Children and Parents compared with the Corresponding Similarity between Children and their Older Siblings: A Frontal view Photographic Study

Chougule

Prasad

Jayade

2013

JIOS

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Objective: The investigation was aimed at studying genetic transmission of soft tissue facial features by comparing the degree of correlation of facial soft tissue features similarities between children and their parents, and children and their older siblings of the same gender, in order to explore the possibility of predicting adult soft tissue form. Materials and methods:The study group comprised of 30 pairs of biologic parents and their 60 children-two children of the same gender per pair such that the older one was more than 18 years of age and the younger one was less than 14 years of age. The control group consisted of 30 pairs of nonrelated parents.Scanned tracings of standardized frontal photographs were used for analyzing four groups of facial parameters. Correlation coefficient was calculated to asses the degree of facial similarity among various pairs.Results: Degree of correlation from the highest to the lowest was seen in the following order: Between the midparents and offspring pairs, mother and older offspring pairs, older sibling and younger offspring pairs (especially for the male sample), father and older offspring pairs and father and younger offspring pairs. Similarity between children and the control group was negligible. Conclusion:There is a fairly strong genetic control in the transmission of soft tissue facial characteristics. The correlations are helpful in forecasting the growth of soft tissue features of children by comparison with the parents or older siblings.

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Section: Possibility Of Forecasting Adult Formcontrasting

confidence: 71%

Facial Soft Tissue Similarity between Children and Parents compared with the Corresponding Similarity between Children and their Older Siblings: A Frontal view Photographic Study

Chougule

Prasad

Jayade

2013

JIOS

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“…3,4 Comparisons between monozygotic and dizygotic twins have revealed even stronger relationships between genetic factors and craniofacial morphology. 5,6 Growth hormone (GH), a peptide hormone produced in the anterior pituitary, plays a major role in regulating growth and development of the maxillofacial complex.…”

Section: Introductionmentioning

confidence: 99%

Growth hormone receptor gene variant and three-dimensional mandibular morphology

Nakawaki

Yamaguchi

Isa

et al. 2016

The Angle Orthodontist

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Objective: To examine the relationship between three-dimensional mandibular morphology and growth hormone receptor (GHR) gene variants in a healthy Japanese population. Materials and Methods: The subjects, who were unrelated Japanese orthodontic patients, consisted of 64 men and 114 women. Using the Taqman genotyping assay, GHR gene rs6184 and rs6180 variants were detected in genomic DNA extracted from saliva. Mandibular volume and length were measured from cone-beam computed tomography images that were analyzed using Analyze image-processing software. The relationship between GHR gene variants and threedimensional mandibular morphology was statistically examined. Results: Statistical significance for the relationship between the distance between the left and right coronoid processes and rs6180 was noted (P , .05). Conclusion: Our results indicate that the GHR variant rs6180 is associated with the distance between the left and right coronoid process in the Japanese subjects. (Angle Orthod. 2017;87:68-73)

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“…1 Until recently, the vast majority of research has focused on the heritability of malocclusion and craniofacial morphology among siblings, with the twin model being the most popular method used. [1][2][3][4][5][6][7][8][9] Research comparing parents with their offspring has been limited because of the fact that tooth loss, restorative, prosthetic, and orthodontic treatment of older generations makes these investigations difficult.…”

Section: Introductionmentioning

confidence: 99%

Cephalometric craniofacial features in Saudi parents and their offspring

Alkhudhairi

Alkofide

2010

The Angle Orthodontist

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Objective: To estimate the correlation and heritability values of craniofacial variables between parents and their offspring. Materials and Methods: The sample comprised 24 Saudi families; each family consisted of father, mother, son, and daughter. Lateral cephalometric radiographs were taken for each family member. Twenty-eight angular, linear, and proportional cephalometric variables were measured. Interfamilial correlations and heritability (h 2 ) values were estimated among father-son, father-daughter, mother-son, and mother-daughter pairings. Results: The most similar angular measurements between parents and offspring were related to mandibular variables, which were as follows: MP-SNu, MP-FHu, SNBu, and SNPogu; facial height dimensions and mandibular body length were among the highest similar linear variables. Lower facial height percentage had greater resemblance to parents with regard to proportional measurements. Both the correlation coefficients and the heritable values of these characteristics were stronger in the father-offspring than the mother-offspring pairings. The daughters' cephalometric craniofacial characteristics were more affected by the parents than were those of the sons. Conclusions: The overall correlation and h 2 mean values for the three types of measurements showed stronger values in the father-offspring than the mother-offspring groups, with the fatherdaughter pairings more significant than the father-son groups.

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The heritability of attained growth in the human face

Cited by 50 publications

References 8 publications

Facial Soft Tissue Similarity between Children and Parents compared with the Corresponding Similarity between Children and their Older Siblings: A Frontal view Photographic Study

Facial Soft Tissue Similarity between Children and Parents compared with the Corresponding Similarity between Children and their Older Siblings: A Frontal view Photographic Study

Growth hormone receptor gene variant and three-dimensional mandibular morphology

Cephalometric craniofacial features in Saudi parents and their offspring

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