The hepatologist in the haematologists' camp

Histopathology of graft versus host disease of the liver

“…The role of histology in the clinical management of L‐GVHD is usually limited to selected situations. Liver biopsy is indicated when one or more causes of liver dysfunction other than L‐GVHD are suspected, or when L‐GVHD occurs in isolation without extrahepatic involvement, or when liver dysfunction does not respond to increased immunosuppression following a clinical diagnosis of L‐GVHD 15,16 . The potential value of liver biopsy in L‐GVHD patients is outweighed by the procedure‐related risk and clinical data (e.g.…”

Fulminant Hepatic Failure Caused by Adenovirus Infection Mimicking Peliosis Hepatitis on Abdominal Computed Tomography Images after Allogeneic Hematopoietic Stem Cell Transplantation

“…Sinusoidal obstruction syndrome and drug-induced hepatotoxicity are frequently observed in the first few weeks after SCT. Subsequently, acute GVHD, viral infection, chronic GVHD, and nodular regenerative hyperplasia develop (10). Adenovirus is one of the causes of fulminant hepatic failure after HSCT.…”

Iatrogenesis or Bad Luck? Relapse of an LMP1-Positive Follicular Lymphoma after Immunosuppression for Hepatitis-Associated Aplastic Anaemia

“…Treatment of patients with a positive PCR for HBV DNA with any of the available agents (interferon-alpha, lamivudine, ganciclovir or famciclovir) has been advocated before stem cell transplantation [15]or chemotherapy for lymphoid malignancies [16]. So probably all chronic HBsAg carriers with detectable HBV DNA about to become immunodepressed should receive primary prophylaxis to prevent reactivation, especially those on steroid treatment or with a negative HBeAg [16], as our patient.…”