Background:Vaccine is an effective method to prevent infectious diseases and their complication. However, immunization coverage has declined drastically in some countries for some reasons. This study aimed to review sytematically the factors associated with the rejection of child immunization. Subjects and Method: This was a systematic review conducted by searching published articles from database including PubMed, Wiley Online Library, JSTOR, SpringerLink, ScienceDirect, ProQuest, Scopus, ResearchGate, and Taylor&Francis. The keywords were "immunization", "vaccination", "rejection", and "children". The inclusion criteria were English and open access. 176 articles were obtained by searching onlie database. After review process 8 articles were including in this review. Result: Vaccination rejection was caused by incomplete information delivered by health workers and social media. Internal factors of parents were including age, experience, and education. External factor was socio-cultural. Misinformation about vaccines from anti-vaccine influenced parents.
Conclusion:Vaccination rejection is caused by incomplete information delivered by health workers and social media. Good health communication, performance of health workers, social media campaign can increase vaccine acceptance.