The heart of darkness

Petter-Puchner, Alexander H.; Fortelny, René H.

doi:10.1007/s10029-014-1336-3

Cited by 3 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, patients are treated with IV antibiotic therapy for few days until the symptoms of infection subside and, only at this point, a definitive closure of the wound with a new mesh material can be attempted [59]. Such a multistage approach can be relatively tedious for the patient as a clean wound situation must be achieved before the final closure, which can take few days to few weeks [60]. Mesh removal is required in 41% of the case of deep SSI [30], and more frequently in patients treated with ePTFE, as this patch cannot be drained efficiently due to its dense and laminated architecture [56].…”

Section: Treatment Of Established Infections Of Hernia Implantsmentioning

confidence: 99%

Infections associated with mesh repairs of abdominal wall hernias: Are antimicrobial biomaterials the longed-for solution?

Guillaume

Pérez‐Tanoira

Fortelny³

et al. 2018

Biomaterials

View full text Add to dashboard Cite

The incidence of mesh-related infection after abdominal wall hernia repair is low, generally between 1 and 4%; however, worldwide, this corresponds to tens of thousands of difficult cases to treat annually. Adopting best practices in prevention is one of the keys to reduce the incidence of mesh-related infection. Once the infection is established, however, only a limited number of options are available that provides an efficient and successful treatment outcome. Over the past few years, there has been a tremendous amount of research dedicated to the functionalization of prosthetic meshes with antimicrobial properties, with some receiving regulatory approval and are currently available for clinical use. In this context, it is important to review the clinical importance of mesh infection, its risk factors, prophylaxis and pathogenicity. In addition, we give an overview of the main functionalization approaches that have been applied on meshes to confer anti-bacterial protection, the respective benefits and limitations, and finally some relevant future directions.

show abstract

Section: Treatment Of Established Infections Of Hernia Implantsmentioning

confidence: 99%