2013
DOI: 10.1186/1472-6963-13-441
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The heart healthy lenoir project-an intervention to reduce disparities in hypertension control: study protocol

Abstract: BackgroundRacial disparities in blood pressure control are well established; however the impact of low health literacy (LHL) on blood pressure has garnered less attention. Office based interventions that are created with iterative patient, practice and community stakeholder input and are rolled out incrementally, may help address these disparities in hypertension control. This paper describes our study protocol.Methods/designUsing a community based participatory research (CBPR) approach, we designed and implem… Show more

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Cited by 28 publications
(42 citation statements)
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“…exhibited hypertension trended lower in subjects who had copies of the minor allele (69%, 64%, and 60% for the C/C, C/T, and T/T genotypes, respectively). Finally, the MAF of the protective T allele in this cohort was dramatically lower in African Americans than in subjects of mixed European descent (6.5% vs. 26.6%; P < 0.001), and sequencing of over 1,000 individuals from this and additional University of North Carolina cardiovascular cohorts (17)(18)(19)(20) confirmed this result (Supplemental Table 2). Identification of regulatory elements within the ARHGAP42 gene.…”
Section: Resultssupporting
confidence: 65%
“…exhibited hypertension trended lower in subjects who had copies of the minor allele (69%, 64%, and 60% for the C/C, C/T, and T/T genotypes, respectively). Finally, the MAF of the protective T allele in this cohort was dramatically lower in African Americans than in subjects of mixed European descent (6.5% vs. 26.6%; P < 0.001), and sequencing of over 1,000 individuals from this and additional University of North Carolina cardiovascular cohorts (17)(18)(19)(20) confirmed this result (Supplemental Table 2). Identification of regulatory elements within the ARHGAP42 gene.…”
Section: Resultssupporting
confidence: 65%
“…Focus groups and other stakeholder engagement activities were held in the formative year to adapt and design our intervention [18, 19]. Stakeholders included people representing patients, clinicians, local government, educational systems, faith communities, health advocacy groups and many others.…”
Section: 0 Materials and Methodsmentioning
confidence: 99%
“…As an overarching framework, we reasoned that implementing activities such as 1) enhancing and standardizing team based care, 2) providing patient self-management support (to improve intermediary measures such as patient activation, medication adherence, disease knowledge), 3) facilitating the provision of clinical data to providers [20, 21] and infusing the principles of health literacy throughout, that blood pressure will be lowered. Further details of the trial design, conceptual framework, and methods have been published [18], (Cene C, Journal of Clinical Hypertension, in press).…”
Section: 0 Materials and Methodsmentioning
confidence: 99%
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“…However, evidence for the effectiveness of multilevel interventions in reducing disparities is limited. 5 Current CPHHD multilevel interventions include a corner store intervention project in East Los Angeles, California 6 ; health system quality improvement projects to reduce hypertension disparities in Baltimore, Maryland, and rural North Carolina 7,8 ; a media training program for community-based organizations and toolkit for journalists to influence the public agenda on tobacco-related health disparities in Lawrence, Massachusetts; and a reservation-wide, multimedia campaign to increase colorectal cancer screening in the Northern Plains. Issues that need to be addressed in multilevel intervention research range from the very definition of what constitutes a multilevel intervention to identifying the best methodologies for intervention design, implementation, analyses, and optimizing translation, dissemination, and sustainability.…”
Section: Test Multilevel Interventionsmentioning
confidence: 99%