The health status of children born through assisted reproductive technologies: probable risks and possible complications

Pitskhelauri, E.G.; Стрижаков, А.Н.; Timokhina, E. B.; Belousova, V. S.; Богомазова, И.М.; Garina, A. O.

doi:10.17749/2313-7347.2018.12.3.056-063

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…Актуальна связь увеличения риска аномалий развития новорожденных с родительскими факторами (бесплодием и его длительностью, возрастом супругов на момент зачатия, их состоянием здоровья). Снижение риска возникновения кардиоваскулярной и других патологий предполагает тщательное обследование и лечение женщин до искусственного оплодотворения, регуляр-ное наблюдение женщины и адекватное ведение беременности, должную пренатальную диагностику [57]. Последняя, как средство профилактики врожденных аномалий, обеспечивает существенное снижение частоты ВПР среди живорожденных детей, в том числе после ВРТ.…”

Section: том 7 №6 / 2020unclassified

Cardiovascular risks in infants born with reproductive technologies

Gorlova

Омельченко

Sokolova

et al. 2020

Transl. med. (Print)

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Russia is on the second place among European countries in the number of completed cycles of assisted reproductive technologies (ART). The proportion of children conceived using ART becomes annually higher. The present review summarises data on the impact of new reproductive technologies on the risk of developing cardiovascular diseases are presented. Potential health risks in the introduction of ART in babies born are discussed in numerous studies, the impact on all stages of embryo- and organogenesis is noted. The greatest problem is a possible increase in the incidence of congenital malformations (CM) in children after ART compared to the latter in the natural population. The frequency of CM is due not only to the use of APT, but also to factors such as genetic characteristics, age and state of health of the mother, aggravated obstetric-gynecological history, multiplicity, low birth weight of the fetus. In children conceived with ART, often appear early symptoms of systemic endothelial dysfunction, metabolic disorders (lipid metabolism, glucose level), congenital heart defects (interventricular septum defect, small cardiac development abnormality (false chord), open arterial duct, open oval window). There is a need to improve prenatal diagnostics of CM in early pregnancy and regular medical examinations of children conceived with ART.

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Section: том 7 №6 / 2020unclassified

Cardiovascular risks in infants born with reproductive technologies

Gorlova

Омельченко

Sokolova

et al. 2020

Transl. med. (Print)

View full text Add to dashboard Cite

show abstract

Assessment of the health status of infants born from women of the late reproductive period

Омарова

Ibragimova²,

Магомедова

et al. 2021

Ross. vestn. perinatol. pediatr.

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Objective. To assess the condition of newborns from women of the late reproductive period (LRP), depending on the parity of births.Material and methods. The authors examined 130 pregnant women and their 130 newborns. Group I consisted of 60 primiparous women of late reproductive period and their 60 newborns, Group II included 40 multiparous women of the late reproductive period and their 40 newborns, Group III (control group) consisted of 30 healthy pregnant women aged from 18 to 25 years and their 30 newborns. The authors performed a retrospective analysis of the gestation course and perinatal outcomes. Ultrasound and neurosonography were used among the instrumental research methods.Results. Women of the late reproductive period gave birth to children in a state of asphyxia twice more often, who develop neurological disorders 1,5 times more often and complex postnatal adaptation and disorders of the perinatal period are twice more likely. Among women of the late reproductive period, primiparous women gave birth to children with the most severe disorders.Conclusion. The high incidence of neurological diseases in children born from women of the late reproductive period is associated with age-related changes in their germ cells, the implementation of assisted reproductive technologies, and the intake of hormonal drugs in early pregnancy. The data obtained should be taken into account by obstetricians in the course of pregnancy in women of late reproductive age; they should be included in the group of high risk of developing neurological disorders in children.

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The health status of children born through assisted reproductive technologies: probable risks and possible complications

Cited by 2 publications

References 30 publications

Cardiovascular risks in infants born with reproductive technologies

Cardiovascular risks in infants born with reproductive technologies

Assessment of the health status of infants born from women of the late reproductive period

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