2023
DOI: 10.1016/j.jaci.2023.01.031
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The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis

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Cited by 2 publications
(1 citation statement)
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“…Li et al reported that connective tissue mast cell (CTMC)-specific Gata2 deficient mice failed to develop IgE/mast cell-mediated anaphylaxis [ 11 ]. Meanwhile, MITF bound to an enhancer located upstream of the transcription start site of the HDC gene and directed enhancer activity [ 12 ]. Thus, targeting HDC expression is a promising alternative to treating allergic diseases.…”
Section: Introductionmentioning
confidence: 99%
“…Li et al reported that connective tissue mast cell (CTMC)-specific Gata2 deficient mice failed to develop IgE/mast cell-mediated anaphylaxis [ 11 ]. Meanwhile, MITF bound to an enhancer located upstream of the transcription start site of the HDC gene and directed enhancer activity [ 12 ]. Thus, targeting HDC expression is a promising alternative to treating allergic diseases.…”
Section: Introductionmentioning
confidence: 99%