The GyneFix® implant systems for interval, postabortal and postpartum contraception: a significant advance in long-term reversible contraception

The ‘frameless’ intrauterine system for long‐term, reversible contraception: A review of 15 years of clinical experience

“…GyneFix is a highly effective intrauterine contraceptive system. Failures range from 0.0/100 users to 2.5/100 users (cumulative rates) during the first year up to 9 years of use (data from published and unpublished randomized and non‐randomized comparative clinical trials 6–9 . The long‐term efficacy has been confirmed in a WHO conducted, randomized comparative clinical trial [Rowe, personal communication].…”

Randomised controlled trial assessing the acceptability of GyneFix<SUP>®</SUP> versus Gyne-T380S<SUP>®</SUP> for emergency contraception

“…In the mid-1980s, in an attempt to reduce these side effects, the International Study Group on Intrauterine Drug Delivery Systems developed a flexible, frameless IUD: the GyneFix ® . 8 Other advantages postulated for this frameless device include a lower expulsion rate due to its anchoring system, 9 less insertion-linked discomfort and less cramping immediately after the insertion because of the absence of a frame.…”

Comparative trial of the force required for, and pain of, removing GyneFix<SUP>®</SUP> versus Gyne-T380S<SUP>®</SUP> following randomised insertion

“…1 It has been marketed in the UK since early 1998, and is currently licensed for 5-year use. Given that the GyneFix is attached to the fundal myometrium, it is likely that removal both requires more force and is associated with more pain than for a framed IUD which 'sits' unattached within the uterine cavity.…”