The Gustatory System of Lampreys

Barreiro‐Iglesias, Antón; Anadón, Ramón; Rodicio, Marı́a Celina

doi:10.1159/000315151

Cited by 26 publications

(16 citation statements)

References 99 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Little is known about the central primary taste centers and their connections in non‐teleost fishes and amphibians. In lampreys, the cellular and neurochemical organization of taste buds has been recently studied, revealing some divergent traits with regard to those of gnathostomes (Barreiro‐Iglesias et al, ). Primary fibers of the lamprey glossopharyngeal and vagal nerves project onto a poorly defined lateral region of the caudal rhombencephalon (Koyama, ), and nothing is known about the ascending connections of this region.…”

Section: Discussionmentioning

confidence: 99%

Gustatory and general visceral centers and their connections in the brain of adult zebrafish: a carbocyanine dye tract‐tracing study

Yáñez

Souto

Piñeiro

et al. 2016

J of Comparative Neurology

Self Cite

View full text Add to dashboard Cite

The central connections of the gustatory/general visceral system of the adult zebrafish (Danio rerio) were examined by means of carbocyanine dye tracing. Main primary gustatory centers (facial and vagal lobes) received sensory projections from the facial and vagal nerves, respectively. The vagal nerve also projects to the commissural nucleus of Cajal, a general visceral sensory center. These primary centers mainly project on a prominent secondary gustatory and general visceral nucleus (SGN/V) located in the isthmic region. Secondary projections on the SGN/V were topographically organized, those of the facial lobe mainly ending medially to those of the vagal lobe, and those from the commissural nucleus ventrolaterally. Descending facial lobe projections to the medial funicular nucleus were also noted. Ascending fibers originating from the SGN/V mainly projected to the posterior thalamic nucleus and the lateral hypothalamus (lateral torus, lateral recess nucleus, hypothalamic inferior lobe diffuse nucleus) and an intermediate cell- and fiber-rich region termed here the tertiary gustatory nucleus proper, but not to a nucleus formerly considered as the zebrafish tertiary gustatory nucleus. The posterior thalamic nucleus, tertiary gustatory nucleus proper, and nucleus of the lateral recess gave rise to descending projections to the SGN/V and the vagal lobe. The connectivity between diencephalic gustatory centers and the telencephalon was also investigated. The present results showed that the gustatory connections of the adult zebrafish are rather similar to those reported in other cyprinids, excepting the tertiary gustatory nucleus. Similarities between the gustatory systems of zebrafish and other fishes are also discussed. J. Comp. Neurol. 525:333-362, 2017. © 2016 Wiley Periodicals, Inc.

show abstract

Section: Discussionmentioning

confidence: 99%

Gustatory and general visceral centers and their connections in the brain of adult zebrafish: a carbocyanine dye tract‐tracing study

Yáñez

Souto

Piñeiro

et al. 2016

J of Comparative Neurology

Self Cite

View full text Add to dashboard Cite

show abstract

“…The sense of taste enables animals to adapt to specific habitats (Oike et al 2007; Ishimaru 2009; Barreiro-Iglesias et al 2010). In vertebrates (Chandrashekar et al.…”

Section: Introductionmentioning

confidence: 99%

Enteroendocrine profile of α-transducin immunoreactive cells in the gastrointestinal tract of the European sea bass (Dicentrarchus labrax)

Latorre

Mazzoni

Giorgio

et al. 2013

Fish Physiol Biochem

View full text Add to dashboard Cite

In vertebrates, chemosensitivity of nutrients occurs through activation of taste receptors coupled with G protein subunits, including α-transducin (Gαtran) and α-gustducin (Gαgust). This study was aimed at characterizing the cells expressing Gαtran-immunoreactivity throughout the mucosa of the sea bass gastrointestinal tract. Gαtran immunoreactive cells were mainly found in the stomach, and a lower number of immunopositive cells were detected in the intestine. Some Gαtran immunoreactive cells in the stomach contained Gαgust immunoreactivity. Gastric Gαtran immunoreactive cells co-expressed ghrelin, obestatin and 5-hydroxytryptamine immunoreactivity. In contrast, Gαtran immunopositive cells did not contain somatostatin, gastrin/cholecystokinin, glucagon-like peptide-1, substance P, or calcitonin gene-related peptide immunoreactivity in any investigated segments of the sea bass gastrointestinal tract. Specificity of Gαtran and Gαgust antisera was determined by Western blot analysis, which identified two bands at the theoretical molecular weight of ~45 and ~40 kDa, respectively, in sea bass gut tissue as well as in positive tissue, and by immunoblocking with the respective peptide, which prevented immunostaining. The results of the present study provide a molecular and morphological basis for a role of taste related molecules in chemosensing in the sea bass gastrointestinal tract.

show abstract

“…Induction of egr -1 mRNA was obvious as early as 15 min after addition of the bitter substance, peaked after 30 min stimulation and decreased thereafter, while control non-stimulated fish exhibited only a faint staining (Figures 3A–D). Labeling in intact larvae was mostly detected in the gills where taste buds are known to be present (Hansen et al, 2002; Barreiro-Iglesias et al, 2010) (Figures 3B–D). In addition, in microtome sections of the head of denatonium-stimulated as compared to non-stimulated larvae, labeling was concentrated in superficial cells of pharyngeal arches (Figure 3F) and oropharyngeal cavity (Figure 3H).…”

Section: Resultsmentioning

confidence: 96%

Egr-1 induction provides a genetic response to food aversion in zebrafish

Boyer¹,

Ernest²,

Rosa³

2013

Front. Behav. Neurosci.

View full text Add to dashboard Cite

As soon as zebrafish larvae start eating, they exhibit a marked aversion for bitter and acidic substances, as revealed by a consumption assay, in which fluorescent Tetrahymena serve as a feeding basis, to which various stimuli can be added. Bitter and acidic substances elicited an increase in mRNA accumulation of the immediate-early response gene egr-1, as revealed by in situ hybridization. Conversely, chemostimulants that did not induce aversion did not induce egr-1 response. Maximum labeling was observed in cells located in the oropharyngeal cavity and on the gill rakers. Gustatory areas of the brain were also labeled. Interestingly, when bitter tastants were repeatedly associated with food reward, zebrafish juveniles learned to ingest food in the presence of the bitter compound. After habituation, the acquisition of acceptance for bitterness was accompanied by a loss of egr-1 labeling. Altogether, our data indicate that egr-1 participates specifically in food aversion. The existence of reward-coupled changes in taste sensitivity in humans suggests that our results are relevant to situations in humans.

show abstract

The Gustatory System of Lampreys

Abstract: research should focus on the central processing of the gustatory information. Here we will review the current knowledge about the gustatory system of lampreys to provide a basis for establishing the direction of further studies of this chemosensory system.

Cited by 26 publications

References 99 publications

Gustatory and general visceral centers and their connections in the brain of adult zebrafish: a carbocyanine dye tract‐tracing study

Gustatory and general visceral centers and their connections in the brain of adult zebrafish: a carbocyanine dye tract‐tracing study

Enteroendocrine profile of α-transducin immunoreactive cells in the gastrointestinal tract of the European sea bass (Dicentrarchus labrax)

Egr-1 induction provides a genetic response to food aversion in zebrafish

Contact Info

Product

Resources

About