2022
DOI: 10.1097/md.0000000000030262
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The growth rates and influencing factors of preterm and full-term infants: A birth cohort study

Abstract: This study aimed to explore the growth rates and influencing factors of the length and weight of preterm and full-term infants in the urban areas of Hubei province to provide a reference for child health and related clinical fields. A birth cohort study was used to analyze the growth rates and influencing factors of the length and weight of preterm and full-term infants using a multivariate regression analysis. The growth rates of the length and weight of preterm infants were significantly lower than those of … Show more

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“…Infants born prematurely show significantly lower weight and length growth rates than those of infants born at full term in the first three months after birth [65]; thus, nutritional interventions that include intravenous amino acid supplementation have been employed immediately after birth to accelerate fat-free mass accretion [66,67]. Unlike insulin, essential amino acids-especially leucine-stimulate the mTOR pathway through their interactions with Ras-related GTP-binding proteins (Rags), thereby activating muscle protein synthesis and fat-free mass accretion [68].…”
Section: Impaired Amino Acid Signaling and Protein Synthesismentioning
confidence: 94%
“…Infants born prematurely show significantly lower weight and length growth rates than those of infants born at full term in the first three months after birth [65]; thus, nutritional interventions that include intravenous amino acid supplementation have been employed immediately after birth to accelerate fat-free mass accretion [66,67]. Unlike insulin, essential amino acids-especially leucine-stimulate the mTOR pathway through their interactions with Ras-related GTP-binding proteins (Rags), thereby activating muscle protein synthesis and fat-free mass accretion [68].…”
Section: Impaired Amino Acid Signaling and Protein Synthesismentioning
confidence: 94%