The growth of the body and organs of the albino rat as affected by feeding various ductless glands (thyroid, thymus, hypophysis, and pineal)

Abstract

Ins ti tutc of Anatomy, niversity of ~Iinnesota A thesis submitted to the faculty of the graduate school of the University of Minnesota in partial fulfilment of the requirements for the degree of Doctor of Philosophy

Adrenal Insufficiency

“…Hewitt (37), however, has pointed out that in certain respects Kuriyama's experiments differed from those of Herring. And other observers, (R. G. Hoskins (38) and especially E. R. Hoskins (39) ) have also obtained adrenal hypertrophy after feeding with thyroid. It is necessary to remark, however, that there is nothing specific about the increase in size of the adrenals, since similar hypertrophy is found in other organs, including the pancreas (E. R. Hoskins (38) Kojima (40) ).…”

The Production of Cardiac Hypertrophy by Thyroxine in the Rat

“…The production of cardiac enlargement experimentally in animals by the administration of thyroid extract has been described by several investigators [Iscovesco, 1913;Hoskins, 1916;Herring, 1917;Cameron and Carmichael, 1920;Goodpasture, 1921;Hashimoto, 1921;Simonds and Brandes, 1930]. The myocardium of these animals frequently showed pathological changes.…”

Effects of exercise upon circulating thyroxine serum and hepatic lipid concentrations, heart, and seminal vesicles in rats and of age and exercise upon circulating thyroxine in humans

“…Several investigators (Hoskins, 1916;Herring, 1917;Hewitt, 1920) found an increase in the size of the heart in rats after they were fed fresh thyroid glands. Later, the feeding of dried thyroid glands (Cameron and Carmichael, 1920) or desiccated thyroid powder (Ullrick and Whitehorn, 1952) resulted in similar findings.…”