The Greatness of Glass

Zitzer, Nina C.

doi:10.1016/j.cvsm.2022.07.005

Cited by 1 publication

(2 citation statements)

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“…The quantification of red blood cells (RBCs), and white blood cells (WBCs) in both healthy and diseased patients is essential, and a complete blood count (CBC) is routinely done to establish a patient evaluation database [1][2][3]. Laboratory tests are conducted for various reasons, including screening tests like CBC on healthy animals as a preventive medicine measure, testing geriatric patients for subclinical disease, and identifying conditions that could make an animal a surgical or anesthetic risk.…”

Section: Introductionmentioning

confidence: 99%

“…MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions, or products referred to in the content. Automated hematology analyzers are commonly used in veterinary reference laboratories and clinics to generate quick and cost-effective CBC results, which can aid in improving patient care [1,3]. The decision to request hematology tests is based on the cost of the test versus the potential benefit to the animal.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Painless Artificial Intelligence Point-of-Care hemogram diagnosis in Companion Animals

Barroso,

Costa,

Gregório

et al. 2024

Preprint

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Quantification of erythrocytes and leukocytes is an essential aspect of hemogram diagno- 23 sis in Veterinary Medicine. Flow cytometry analysis, laser scattering, and impedance detection are 24 standard laboratory techniques, verified by manual microscopy counting. Although single-cell scat- 25 tering is already used as a standard technology for differentiating cell counts in flow cytometry, it 26 requires capillary cell separation. The current study investigates the scattering characteristics of 27 whole blood to identify correlations with erythrocytes and leukocytes counts. The scattering infor- 28 mation present in blood samples can be classified into three types: i) geometrical scattering, which 29 occurs when non-absorbed light is reflected and scattered, ii) Mie scattering, which happens when 30 light is scattered by particles of a similar size to the wavelength, and iii) Rayleigh scattering, which occurs when light is scattered by particles that are smaller than the incident light wavelength. In 32 this study, we investigate the scattering correction coefficients of dog blood absorption spectra in 33 the visible-near infrared range, to establish direct correlations with erythrocytes and leukocytes 34 counts, using multivariate linear regression. Our findings demonstrate the possibility of using the 35 scattering properties of dog blood, which is a step towards the existence of a portable and miniatur- 36 ized hemogram diagnosis in Veterinary Clinics worldwide.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%