The Gore-Tex prosthetic ligament as a salvage procedure in deficient knees

Abstract

The purpose of this study was to evaluate the results of prosthetic ligament replacement of the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) with the Gore-Tex polytetrafluorethyene prosthesis (W.L. Gore and Co., Flagstaff, Ariz. ) in 52 patients (54 knees). All patients sustained multiple (failed) knee operations or had knees with gross instability. Twenty-eight (29 knees) of the 52 patients (54%) in whom the Goretex prosthesis was still in situ were available at a minimum follow-up of 5 years (mean 9 years, range 5-11 years). The mean age at examination was 39 years (range 30-57 years); there were 15 men and 13 women. The results of the procedure were compared with the results of the same patients at a mean follow-up of 3 years. Eighty-one percent of the patients of the whole group complained about pain. This was 78% for the patients with an ACL reconstruction and 75% for the patients with a PCL reconstruction. The Tegner activity score and the Lysholm knee score showed a statistically significant difference over time. The anterior instability pattern improved in only 43% of the knees and the posterior instability in 41% of the knees. The Lachman test showed also a significant difference over time. In all patients X-ray showed an increase in degenerative changes. In conclusion, the PTFE prosthetic ligament in the reconstruction of the ACL and the PCL in the (chronically) unstable knee seems to deteriorate over time.

Failure of acromioclavicular reconstruction using Gore-Tex graft due to aseptic foreign-body reaction and clavicle osteolysis: A case report

“…54 Although the only clinical report in which Gore-Tex was used for CC stability showed good results, 41 complications associated with Gore-Tex implants have been reported in other orthopaedic applications, particularly ACL reconstruction. Although early reports on the use of Gore-Tex for ACL reconstruction were encouraging, [7][8][9]17,31,53 other studies showed mixed results with high failure rates, 18,19,45,47,58 often associated with tibial and femoral osteolysis. The exact mechanism of osteolysis seen with Gore-Tex implants is not known.…”

The Effects of Co‐Immobilization of Epidermal Growth Factor and Adhesion Factor on the Proliferation of Ligament Cell

“…[6][7][8] Permanent synthetic ACL prosthesis including Gore-Tex prosthesis, Stryker-Dacron ligament, and Kennedy ligament augmentation device can be used, and may show satisfactory performance in the short term but they tend to deteriorate and fail in the long term. [9][10][11] In addition, a prosthesis-induced disturbance in the release of cytokine by lymphocytes can cause defects in the host defense against a bacterial infection. various growth factors have been reported.…”

Tissue Engineering of the Anterior Cruciate Ligament and Meniscus Using Acellularized Scaffolds

“…Most of the prostheses used for ACL reconstruction have failed as they showed an adverse effect on the cartilage and caused in some cases a marked synovialitis. Though their biomechanical Properties were excellent initially, most of the prostheses had the problem of degradation, tunnel widening and high failure rates after several years (Muren et al, 2005;Roolker et al, 2000). Compared to the biomechanical properties of ligaments, meniscus tissue is even more complex and not surprising, the middle to long term results of the artificial meniscus constructs show different results from one study to the other, but in general do not reach the anatomic, biomechanical results (Buma et al, 2007).…”