The Gore Cardioform Atrial Septal Defect Occluder: A novel solution to the management of severe hemolysis following transcatheter septal defect closure

Naimi, Iman; Jones, Thomas K.; Steinberg, Zachary L.

doi:10.1002/ccd.30144

Cited by 2 publications

(2 citation statements)

References 14 publications

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“… 6 To our knowledge there is only one case report of using a GCA out with the atrial septum in a patient with an iatrogenic Gerbode defect where percutaneous closure with an Amplatzer Muscular VSD Occluder resulted in severe haemolysis. 7 Our experience confirms that GCA could be a preferable choice in selected patients at risk for residual shunting through high-velocity defects.…”

Section: Discussionsupporting

confidence: 75%

Post-myocardial infarction ventricular septal defect closure with Gore Cardioform atrial septal defect occluder to improve tissue interactions: case report

Hribernik

Bentham

2023

European Heart Journal - Case Reports

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Background Gore Cardioform Atrial Septal Defect Occluder (GCA) is composed of a platinum-filled nitinol wire frame covered with expanded polytetrafluoroethylene (ePTFE). This makes the device highly occlusive and resistant to residual shunt through the device, as well as conforming well to the surrounding anatomy. In defects with poor rims to hold a device for closure or where one of the ‘rims’ is the free wall of the left ventricle, such as in a post-infarct apical ventricular septal defect (VSD), successful closure with standard nitinol mesh devices is unlikely. Case summary We present occlusion of a post-myocardial infarction VSD with GCA in a critically ill patient at risk for closure failure and intravascular haemolysis with conventional nitinol mesh devices. The device conforms well to the anatomy even in the absence of apical interventricular septum. Discussion GCA can be used for intracardiac high velocity shunts in selected cases where conventional devices failed due to haemolysis or poor tissue interactions. With growing experience using GCA for closure of atrial septal defects, interventionists should acknowledge the potential advantages of ePTFE material and apply them to other lesions where these could be beneficial for the patients.

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Section: Discussionsupporting

confidence: 75%

Post-myocardial infarction ventricular septal defect closure with Gore Cardioform atrial septal defect occluder to improve tissue interactions: case report

Hribernik

Bentham

2023

European Heart Journal - Case Reports

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“…In addition, hemolysis has been reported after transcatheter occlusion. Hemolysis may be transient, due to device thrombosis and endothelialization, or persistent, leading to acute kidney injury and ultimately to surgical removal of the device [ 75 ]. The supportive wire frame and looser mesh fabric weave, leading to red blood cell shearing, are thought to be the cause of the more frequent occurrence of hemolysis using Amplatzer occluders [ 75 ].…”

Section: Resultsmentioning

confidence: 99%

Congenital Gerbode Defect: A Left Ventricular to Right Atrial Shunt—State-of-the-Art Review of Its General Data, Diagnostic Modalities, and Treatment Strategies

Winter,

Strizek,

Recker

2024

JCDD

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The congenital Gerbode defect is defined as an abnormal communication between the left ventricle and the right atrium. This review aimed to summarize existing evidence, shed light on the clinical implications, and identify knowledge gaps. The systematic literature search was conducted in the PubMed and Google Scholar medical databases using specifically selected keywords. The inclusion of each publication was assessed according to predefined eligibility criteria based on the PICOM (Population, Phenomenon of Interest, Context, Methodology) schema. Titles and abstracts were screened independently by two authors. Available full-text versions of included publications were reviewed and relevant information was extracted. A total of 78 reports were included. The compilation of all congenital Gerbode defect cases described in the literature revealed a variety of clinical presentations comprising dyspnea, palpitations, growth retardation, and asymptomatology. A suitable multimodal diagnostic approach for newborns consists of auscultation, TTE, and optionally TEE and MRI. Because of its rarity, diversity of findings, unknown pathophysiology, and similarity to more common cardiac diseases, the diagnostic challenge remains significant. To prevent untreated long-term sequelae, early individualized treatment is recommended. Surgical defect closure is preferred to device closure for evidence reasons, although major developments are currently taking place. In conclusion, the congenital Gerbode defect provides a diagnostic challenge for pediatricians to allow early diagnosis and intervention in order to improve patients’ quality of life.

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The Gore Cardioform Atrial Septal Defect Occluder: A novel solution to the management of severe hemolysis following transcatheter septal defect closure

Cited by 2 publications

References 14 publications

Post-myocardial infarction ventricular septal defect closure with Gore Cardioform atrial septal defect occluder to improve tissue interactions: case report

Post-myocardial infarction ventricular septal defect closure with Gore Cardioform atrial septal defect occluder to improve tissue interactions: case report

Congenital Gerbode Defect: A Left Ventricular to Right Atrial Shunt—State-of-the-Art Review of Its General Data, Diagnostic Modalities, and Treatment Strategies

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