“…Evidence is accumulating that distinct sets of effector genes are coordinately expressed in successive waves during the course of host infection, reflecting the complexity of effector gene regulation and the diversity of TFs and cis ‐regulatory sequences (Dong et al., 2015; Farfsing et al., 2005; Gervais et al., 2017; Hacquard et al., 2013; Kleemann et al., 2012; Lanver et al., 2018; O’Connell et al, 2012; Soyer et al., 2014; Wang et al., 2011). Fungal genomes collectively contain at least 36 different families of TFs, and 13 TFs from four families are known for their roles in effector regulation (Lin et al., 2018; Tan & Oliver, 2017). M. oryzae is predicted to contain a total of 495 TFs (4.5% of the 11,054 proteins in M. oryzae ) (Park et al., 2013), and thus far MoGti1 is the only TF known to regulate the expression of M. oryzae effector genes, including PWL2 (Li et al., 2016).…”