Abstract:Background Advanced chronic obstructive pulmonary disease (COPD) often leads to hospitalisation and invasive aspergillosis (IA) is a serious complication. Aspergillus sensitisation may worsen symptoms in COPD. In 2016, the global estimate of COPD was 251 million affected. Methods We identified published papers between January 2000 and May 2019 with >50 subjects and GOLD criteria for grade II, III or IV (FEV1/FVC <70% and FEV1 <80%) using spirometry. Given limited data, a conservative 10.5% estimate of… Show more
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