The Global HIV Epidemics among Men Who Have Sex with Men

Beyrer, Chris; Wirtz, Andrea L.; Walker, Damian; Johns, Benjamin; Sifakis, Frangiscos; Baral, Stefan

doi:10.1037/e600032012-001

Cited by 58 publications

(78 citation statements)

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“…Heterosexual transmission is the next most common exposure category, accounting for one-quarter of all diagnoses (306,966). Sex between men is associated with just over one-in-ten (138,286) of diagnosed infections reported. Mother-to-child transmission, receipt of contaminated transfusions and blood products, and nosocomial infections accounted for around 1% of reported diagnoses.…”

Section: Cumulative Number Of Reported Hiv Diagnosesmentioning

confidence: 99%

HIV Epidemics in the European Region: Vulnerability and Response

Platt¹,

Jolley²,

Hope³

et al. 2015

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Section: Cumulative Number Of Reported Hiv Diagnosesmentioning

confidence: 99%

HIV Epidemics in the European Region: Vulnerability and Response

Platt¹,

Jolley²,

Hope³

et al. 2015

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“…Men who have sex with men (MSM) are disproportionately affected by the human immunodeficiency virus (HIV) compared to the general population in nearly all countries reliably collecting surveillance data [1,2]. MSM have 19.3-fold greater odds of being infected with HIV compared with the general population in low-and middle-income country settings [3].…”

Section: Introductionmentioning

confidence: 99%

HIV Treatment Cascades that Leak: Correlates of Drop-off from the HIV Care Continuum among Men who have Sex with Men Worldwide

et al. 2014

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“…The full HASTE analysis supporting Figure 4 is included in the World Bank report, "The Global HIV Epidemics Among Men Who Have Sex with Men." 32 Figure 4 summarizes the interventions assessed, demonstrating that few of these interventions have been tested with RCT, although many are considered the standard of care rendering RCT level of evidence unattainable. Even fewer of these interventions have been tested in LMIC, where the risk environment is often heightened because of stigma and discrimination.…”

Section: Discussionmentioning

confidence: 99%

“…The results of this process are presented in Figure 4, although the complete information and rationale for selection are available in the World Bank report by Beyrer et al 32 Figure 4 also presents an analysis of which interventions are supported by RCTs in both high-income countries and LMIC, as defined by the World Bank Atlas Method. 33 The only interventions evaluated using RCTs in LMIC are individualized riskreduction counseling, brief client-focused counseling, community-level interventions, and preexposure prophylaxis.…”

Section: Combination Hiv Prevention Interventions For Msmmentioning

confidence: 99%

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The Highest Attainable Standard of Evidence (HASTE) for HIV/AIDS Interventions: Toward a Public Health Approach to Defining Evidence

Baral¹,

Wirtz

Sifakis

et al. 2012

Public Health Rep

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Objectives. Evidence-driven decisions have become a standard for health interventions, policy, and programs. While randomized controlled trials (RCTs) are encouraged for public health interventions, there are limitations with RCTs as the gold standard of evidence for HIV interventions. We developed a novel system of evaluating evidence for assessing HIV preventive interventions termed the Highest Attainable Standard of Evidence (HASTE).Methods. The HASTE system focuses on triangulation of three distinct categories of evidence: efficacy data, implementation data, and plausibility. We conducted systematic reviews, including experimental and observational data, to assess all available interventions for men who have sex with men (MSM). We collected implementation and programmatic data using a global electronic consultation, Internet searches, and in-person consultations. We assessed plausibility with expert analyses of both biological and public health evidence.results. HASTE includes four grades of evidence: Strong (Grade 1), Conditional (Grade 2), Insufficient (Grade 3), and Inappropriate (Grade 4). We used the HASTE system to evaluate the evidence for HIV interventions for MSM in low-and middle-income countries. Several differences emerged in the strength of recommendation with the use of the HASTE system, including strong recommendations for voluntary counseling and testing and for structural interventions.conclusions. The HASTE system addresses a need for an evidence evaluation tool that is specific for HIV interventions and facilitates an evaluation of biomedical, behavioral, and structural approaches using the highest standard of attainable evidence. HASTE represents a tool that balances scientific integrity and practicality in assessing the quality of evidence of preventive interventions targeting the most-at-risk populations for HIV.

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The Global HIV Epidemics among Men Who Have Sex with Men

Cited by 58 publications

References 0 publications

HIV Epidemics in the European Region: Vulnerability and Response

HIV Epidemics in the European Region: Vulnerability and Response

HIV Treatment Cascades that Leak: Correlates of Drop-off from the HIV Care Continuum among Men who have Sex with Men Worldwide

The Highest Attainable Standard of Evidence (HASTE) for HIV/AIDS Interventions: Toward a Public Health Approach to Defining Evidence

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