The Gesture Imitation in Alzheimer’s Disease Dementia and Amnestic Mild Cognitive Impairment

Li, Xudong; Jia, Shaowei; Zhou, Zhi; Hou, Chunlei; Zheng, Wenjing; Rong, Pei; Jiao, Jinsong

doi:10.3233/jad-160218

Cited by 10 publications

(14 citation statements)

References 28 publications

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“…Item 1 only involved complex finger gestures, Items 2 and 3 had finger and hand movements involving body midline crossing, and Item 4 had a more complex reversal of hand movements, which made the gesture sequential. Item 4 was the best discriminator in detecting ADD among all of the gestures in our previous study (2). Item 4 was also a better indicator for diagnosing DLB, and Item 1 had good specificity.…”

Section: Figurementioning

confidence: 53%

“…The gesture imitation test is a test that involves the imitation of meaningless gestures, which is considered a form of praxis and evaluates visuospatial and visuomotor abilities as individuals copy hand positions. The test is a useful tool for discriminating between patients with ADD, even patients with mild ADD, and healthy controls, according to our previous study (2). The test is not only correlated with the general neuropsychological tests and the Clinical Dementia Rating (CDR) but also correlated with the clock drawing test (CDT) and the pentagon part of the Mini-Mental State Examination (MMSE), which reflect impairment in visuospatial function.…”

Section: Introductionmentioning

confidence: 91%

“…The instruction was repeated if necessary. The methods were administered according to those in our previous paper (2). Item 1 was performed with fingers III touching the thumb on flexion of the metacarpophalangeal joints with fingers II, IV, and V extended upward.…”

Section: The Gesture Imitation Testmentioning

confidence: 99%

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The gesture imitation test in dementia with Lewy bodies and Alzheimer's disease dementia

Shen

Han

et al. 2022

Front. Neurol.

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ObjectivesDementia with Lewy bodies (DLB) is the second most common type of neurodegenerative dementia following Alzheimer's disease dementia (ADD). This study investigated the diagnostic role of the gesture imitation test in detecting DLB and differentiating DLB from ADD.MethodsA total of 63 patients with DLB, 93 patients with ADD, and 88 healthy controls were included in this study. All participants were administered the gesture imitation test, the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the clock drawing test (CDT), and other neuropsychological tests.ResultsThe patients with DLB performed worse than the healthy controls in the global scores and on every item of the gesture imitation test (p < 0.001). The area under the curve (AUC) for the global scores was 0.889 (p < 0.001) in differentiating the DLB and control groups. Item 4 was a better discriminator, with a sensitivity of 79.37% and a specificity of 79.55%. The AUC for the global scores decreased to 0.593 and the difference was marginal (p = 0.079) in differentiating the DLB and ADD groups. The patients with DLB performed worse on Items 1 and 4 compared with the patients with ADD (p = 0.040, 0.004). The gesture imitation test was positively correlated with the scores of the MMSE (r = 0.355, p = 0.017), the MoCA (r = 0.382, p = 0.010), and the CDT (r = 0.407, p = 0.005) in patients with DLB.ConclusionThe gesture imitation test is an easy, rapid tool for detecting DLB and has a role in differentiating DLB from ADD, especially in Items 1 and 4.

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Section: Figurementioning

confidence: 53%

Section: Introductionmentioning

confidence: 91%

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The gesture imitation test in dementia with Lewy bodies and Alzheimer's disease dementia

Shen

Han

et al. 2022

Front. Neurol.

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“…Recently, several studies have reported the usefulness of gesture imitation tasks for assessing visuospatial/visuoconstructive function in the screening and differential diagnosis of dementia. [9][10][11][12][13][14][15][16][17] Gesture imitation is a simple task which requires the examinee to imitate finger configurations and hand postures made by the examiner. Compared with the figure-copying tasks, gesture imitation tasks have the advantage of being performed easily at the bedside, without the requirement for writing tools.…”

Section: Introductionmentioning

confidence: 99%

Gesture imitation performance in community‐dwelling older people: assessment of a gesture imitation task in the screening and diagnosis of mild cognitive impairment and dementia

Takasaki,

Hashimoto,

Fukuhara

et al. 2024

Psychogeriatrics

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BackgroundGesture imitation, a simple tool for assessing visuospatial/visuoconstructive functions, is reportedly useful for screening and diagnosing dementia. However, gesture imitation performance in healthy older adults is largely unknown, as are the factors associated with lower performance. To address these unknowns, we examined the gesture imitation performance of a large number of community‐dwelling older adults aged ≥65 years in Arao City, Kumamoto Prefecture (southern Japan).MethodsThe examiner presented the participants with eight gesture patterns and considered it a success if they could imitate them within 10 s. The success rate of each gesture imitation was calculated for three diagnostic groups: cognitively normal (CN) (n = 1184), mild cognitive impairment (MCI) (n = 237), and dementia (n = 47). Next, we reorganised the original gesture imitation battery by combining six selected gestures with the following scoring method: if the participants successfully imitated the gestures, immediately or within 5 s, two points were assigned. If they succeeded within 5–10 s, one point was assigned. The sensitivity and specificity of the battery were investigated to detect the dementia and MCI groups. Factors associated with gesture imitation battery scores were examined.ResultsExcept one complex gesture, the success rate of imitation in the CN group was high, approximately 90%. The sensitivity and specificity of the gesture imitation battery for discriminating between the dementia and CN groups and between the MCI and CN groups were 70%/88%, and 45%/75%, respectively. Ageing, male sex, and a diagnosis of dementia or MCI were associated with lower scores on the gesture imitation battery.ConclusionGesture imitation tasks alone may not be sufficient to detect MCI. However, by combining gestures with set time limits, gesture imitation tasks can be a low‐burden and effective method for detecting dementia, even in community medicine, such as during health check‐ups.

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“…However, patients with dementia have difficulty comprehending commands or imitating gestures (Vuorinen et al, 2000 ; Wheaton and Hallett, 2007 ). In addition to memory disorder, patients may also experience visuospatial analysis impairment (Rousseaux et al, 2012 ) and imitation gesture impairment (Nagahama et al, 2015 ; Li et al, 2016 ). In patients with all types of dementia, several kinds of apraxia are seen in the early stages of the disease (Chandra et al, 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Drum Communication Program Intervention in Older Adults With Cognitive Impairment and Dementia at Nursing Home: Preliminary Evidence From Pilot Randomized Controlled Trial

Miyazaki¹,

Okuyama

Mori³

et al. 2020

Front. Aging Neurosci.

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Introduction: Inactivity and consequent deterioration of cognitive and physical function is a major concern among older adults with the limited walking ability and need a high level of care in nursing homes. We aimed to test whether a drumming communication program (DCP) that uses the rhythmic response function of the elderly with cognitive impairment, dementia, and other debilitating disorders would improve their cognitive and physical function. Methods: We conducted a Randomized Controlled Trial (RCT) to investigate the effects of the DCP in 46 nursing home residents who needed high levels of nursing care. The participants were randomly assigned to an intervention and control group. The intervention group attended 30 min of the DCP thrice a week for 3 months. Cognitive function was measured using the Mini-Mental State Examination-Japanese (MMSE-J) and Frontal Assessment Battery (FAB). Physical function was measured using grip strength and active upper limb range of motion with the dominant hand. Body composition was measured using bioelectrical impedance analysis (BIA). These measures were analyzed before and after the DCP intervention period, and data for the two groups were compared thereafter. Results: Initially, the participants had low scores on the MMSE-J, and 84.78% of them used wheelchairs. Following the DCP intervention, the MMSE-J and FAB scores of the DCP group improved significantly. In terms of motor function, the active range of motion of the wrist palmar and the shoulder flexion improved in the intervention group. Regarding body composition, the skeletal muscle mass index, total body protein, and the dominant hand muscle mass that was adding physical load decreased.

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The Gesture Imitation in Alzheimer’s Disease Dementia and Amnestic Mild Cognitive Impairment

Abstract: The gesture imitation test is an easy, rapid tool for detecting ADD, and is suitable for the patients suspected of mild ADD and aMCI in outpatient clinics.

Cited by 10 publications

References 28 publications

The gesture imitation test in dementia with Lewy bodies and Alzheimer's disease dementia

The gesture imitation test in dementia with Lewy bodies and Alzheimer's disease dementia

Gesture imitation performance in community‐dwelling older people: assessment of a gesture imitation task in the screening and diagnosis of mild cognitive impairment and dementia

Drum Communication Program Intervention in Older Adults With Cognitive Impairment and Dementia at Nursing Home: Preliminary Evidence From Pilot Randomized Controlled Trial

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