The German S3 guidelines on dementia

Jessen, Frank; Bohr, Lara; Kruse, Christopher; Dodel, Richard

doi:10.1007/s00115-023-01492-6

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Timely diagnosis of Alzheimer's disease is a key objective, as interventions and novel pharmacological treatment approaches shift to the disease's early stages [1,2]. It is the primary care physicians who often have the closest contact with their patients and who serve as the patient's initial contact point when they seek clarification for perceived changes in cognitive abilities.…”

Section: Introductionmentioning

confidence: 99%

Acceptance of unsupervised app-based cognitive assessment in outpatient care (Preprint)

Blotenberg,

Boekholt,

Lieberknecht

et al. 2024

Preprint

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BACKGROUND The use of unsupervised, app-based cognitive assessments provides considerable opportunities for early and comprehensive testing for Alzheimer’s disease, minimizing the demand on time and personnel resources in medical practices. However, the acceptance of such an app within healthcare has yet to be assessed. OBJECTIVE In this pilot study, we examined the acceptance of an app-based, repeated cognitive assessment for early symptoms of Alzheimer’s disease (neotivCare) in the outpatient care setting from both physicians’ and patients’ perspectives. METHODS Fifteen primary care practices participated, where patients with self- or relative-reported memory problems could be prescribed an app for comprehensive cognitive testing. Patients used the app to test their episodic memory function weekly for three months at home. After the testing period and the final consultation, physicians and patients received questionnaires to assess the app’s acceptance. RESULTS We received completed questionnaires from physicians for 45 patients. Additionally, we received 45 completed questionnaires from the patients themselves. The physicians reported that, for most patients, the app supported their decision-making in the diagnostic process (58%). Additionally, most physicians found the app’s information dependable (75%) and felt more certain in their decisions (84%). From the patients’ perspective, a majority felt thoroughly tested (76%), and only a few considered the time commitment for the cognitive tests to be too burdensome (15%). Moreover, despite the weekly cognitive testing and the lengthy twelve-week testing period, a majority of patients participated in all tests (72%). CONCLUSIONS Our pilot study indicates a high acceptance of an app for unsupervised, app-based cognitive testing over an extended period from both the participating physicians’ and patients’ perspectives. These initial findings suggest that unsupervised app-based cognitive assessment can be integrated into healthcare. CLINICALTRIAL not applicable

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Section: Introductionmentioning

confidence: 99%

Acceptance of unsupervised app-based cognitive assessment in outpatient care (Preprint)

Blotenberg,

Boekholt,

Lieberknecht

et al. 2024

Preprint

View full text Add to dashboard Cite

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Spinal dementia: Don’t miss it, it’s treatable

Urbach,

El Rahal,

Wolf

et al. 2024

Neuroradiology

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Background & purpose Around 5% of dementia patients have a treatable cause. To estimate the prevalence of two rare diseases, in which the treatable cause is at the spinal level. Methods A radiology information system was searched using the terms CT myelography and the operation and classification system (OPS) code 3-241. The clinical charts of these patients were reviewed to identify patients with a significant cognitive decline. Results Among 205 patients with spontaneous intracranial hypotension (SIH) and proven CSF leaks we identified five patients with a so-called frontotemporal brain sagging syndrome: Four of those had CSF venous fistulas and significantly improved by occluding them either by surgery or transvenous embolization. Another 11 patients had infratentorial hemosiderosis and hearing problems and ataxia as guiding symptoms. Some cognitive decline was present in at least two of them. Ten patients had ventral dural tears in the thoracic spine and one patient a lateral dural tear at C2/3 respectively. Eight patients showed some improvement after surgery. Discussion It is mandatory to study the (thoracic) spine in cognitively impaired patients with brain sagging and/ or infratentorial hemosiderosis on MRI. We propose the term spinal dementia to draw attention to this region, which in turn is evaluated with dynamic digital subtraction and CT myelography.

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The German S3 guidelines on dementia

Cited by 2 publications

References 12 publications

Acceptance of unsupervised app-based cognitive assessment in outpatient care (Preprint)

Acceptance of unsupervised app-based cognitive assessment in outpatient care (Preprint)

Spinal dementia: Don’t miss it, it’s treatable

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