The GeoForm annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy☆☆☆

Bonis, Michele De; Taramasso, Maurizio; Grimaldi, Antonio; Maisano, Francesco; Calabrese, Maria; Verzini, Alessandro; Ferrara, David; Alfieri, Ottavio

doi:10.1016/j.ejcts.2010.11.048

Cited by 30 publications

(39 citation statements)

References 19 publications

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“…When surgery is performed in this HF population, repair with undersized ring annuloplasty rather than replacement of the mitral valve is usually preferred; however, its safety and effectiveness have not been well established, and the potential occurrence of valve stenosis has been reported (7). In addition, to the best of our knowledge, there have been no reported morbidity and mortality data in CRT nonresponders undergoing mitral valve surgery.…”

mentioning

confidence: 83%

Correction of Mitral Regurgitation in Nonresponders to Cardiac Resynchronization Therapy by MitraClip Improves Symptoms and Promotes Reverse Remodeling

Auricchio

Schillinger

Meyer

et al. 2011

Journal of the American College of Cardiology

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238

148

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mentioning

confidence: 83%

Correction of Mitral Regurgitation in Nonresponders to Cardiac Resynchronization Therapy by MitraClip Improves Symptoms and Promotes Reverse Remodeling

Auricchio

Schillinger

Meyer

et al. 2011

Journal of the American College of Cardiology

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238

148

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“…For functional MR, the MitraClip is emerging as a valuable alternative, because surgical risk is usually high (37), although the EVEREST data are missing in this field. Compared with outcomes of degenerative patients (38), survival benefit after surgery has not yet been demonstrated (39), and the repair is less durable (40).…”

Section: The Mitraclip: Clinical Experience From First-in-man To Commmentioning

confidence: 98%

The Evolution From Surgery to Percutaneous Mitral Valve Interventions

Maisano¹,

Canna²,

Colombo³

et al. 2011

Journal of the American College of Cardiology

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114

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The edge-to-edge technique is a versatile procedure for mitral valve repair. Its technical simplicity has been the prerequisite for the development of a number of transcatheter technologies to perform percutaneous mitral valve repair. The evolution from a standard open heart surgical to percutaneous procedure involved the application of the technique in minimally invasive robotic surgery and direct access (transatrial) off-pump suture-based repair and finally in the fully percutaneous approach with either suture-based or device (clip)-based approach. The MitraClip (Abbott Vascular, Menlo Park, California) is currently available for clinical use in Europe, and it is mainly applied to treat high-risk patients with functional mitral regurgitation. A critical review of the surgical as well as the early percutaneous repair data is necessary to elucidate the clinical role and the potential for future developments of the edge-to-edge repair in the treatment of mitral regurgitation.

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“…A large variety of mitral annuloplasty systems are available with rings designed to recreate the normal valve saddle shape [18, 19], rings that significantly reduce the septolateral dimension of the annulus [20] and asymmetric ring shapes proposed for ischemic mitral regurgitation. [21] Stiffness ranges from flexible to semi-rigid to stiff, and in each case a range of sizes are available.…”

Section: Commentmentioning

confidence: 99%

Measurement of Mitral Leaflet and Annular Geometry and Stress After Repair of Posterior Leaflet Prolapse: Virtual Repair Using a Patient-Specific Finite Element Simulation

Ge¹,

Morrel²,

Ward³

et al. 2014

The Annals of Thoracic Surgery

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Background Recurrent mitral regurgitation after mitral valve (MV) repair for degenerative disease occurs at a rate of 2.6% per year and re-operation rate progressively reaches 20% at 19.5 years. We believe that MV repair durability is related to initial post-operative leaflet and annular geometry with subsequent leaflet remodeling due to stress. We tested the hypothesis that MV leaflet and annular stress is increased after MV repair. Methods Magnetic resonance imaging was performed before and intra-operative 3D trans-esophageal echocardiography was performed before and after repair of posterior leaflet (P2) prolapse in a single patient. The repair consisted of triangular resection and annuloplasty band placement. Images of the heart were manually co-registered. The left ventricle and MV were contoured, surfaced and a 3D finite element (FE) model was created. Elements of the P2 region were removed to model leaflet resection and virtual sutures were used to repair the leaflet defect and attach the annuloplasty ring. Results The principal findings of the current study are 1) FE simulation of MV repair is able to accurately predict changes in MV geometry including changes in annular dimensions and leaflet coaptation, 2) average posterior leaflet stress is increased, and 3) average anterior leaflet and annular stress are reduced after triangular resection and mitral annuloplasty. Conclusions We successfully conducted virtual mitral valve prolapse repair using FE modeling methods. Future studies will examine the effects of leaflet resection type as well as annuloplasty ring size and shape.

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The GeoForm annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy☆☆☆

Cited by 30 publications

References 19 publications

Correction of Mitral Regurgitation in Nonresponders to Cardiac Resynchronization Therapy by MitraClip Improves Symptoms and Promotes Reverse Remodeling

Correction of Mitral Regurgitation in Nonresponders to Cardiac Resynchronization Therapy by MitraClip Improves Symptoms and Promotes Reverse Remodeling

The Evolution From Surgery to Percutaneous Mitral Valve Interventions

Measurement of Mitral Leaflet and Annular Geometry and Stress After Repair of Posterior Leaflet Prolapse: Virtual Repair Using a Patient-Specific Finite Element Simulation

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