The genus Polygonum: An updated comprehensive review of its ethnomedicinal, phytochemical, pharmacological activities, toxicology, and phytopharmaceutical formulation

Idoudi, Sourour; Tourrette, Audrey; Bouajila, Jalloul; Romdhane, Mehrez; Elfalleh, Walid

doi:10.1016/j.heliyon.2024.e28947

Cited by 1 publication

(1 citation statement)

References 198 publications

(321 reference statements)

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“…Caffeic acid Metabolic effects: antidiabetic; other effects: antidepressant, anticancer, and antiviral [35,36] Chlorogenic acid Metabolic effects: anti-inflammatory, antioxidant, and antidiabetic [37,38] Enhydrin Metabolic effects: antidiabetic and antioxidant; other effects: antimicrobial [39,40] Ferulic acid Metabolic effects: antidiabetic; other effects: antimicrobial and anti-carcinogenic [41,42] Melampolide Metabolic effects: antioxidant and reduces angiogenesis; other effects: antimicrobial, inhibition of DNA synthesis, and increased cell apoptosis [43,44] Phenolic acid Metabolic effects: anti-inflammatory, antidiabetic, and antioxidant; other effects: antimicrobial and anticancer [45,46] Uvedafolin Metabolic effects: antidiabetic and anti-inflammatory; other effects: anti-bacterial (against Anthracis and MRSA) and anticancer [47,48] Additionally, some studies suggest that yacon may help protect the liver from damage caused by toxic substances, also due to the antioxidant and anti-inflammatory properties [8,49].…”

Section: Bioactive Compound Biological Effects Referencesmentioning

confidence: 99%

Effects of Smallanthus sonchifolius Flour on Metabolic Parameters: A Systematic Review

Silva,

Bragante,

Junior

et al. 2024

Pharmaceuticals

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Smallanthus sonchifolius, popularly known as yacon, is a member of the Asteraceae family. Due to its medicinal and edible value, yacon is consumed by different populations. Yacon is unique due to its high fructo-oligosaccharide and inulin content, as well as flavonoids, sesquiterpene lactones, and phenolic acids. Roots can be used to produce flour, which is less perishable and can be applied in various industrial products. This systematic review focuses on the effects of yacon flour on metabolic parameters. PubMed, Cochrane, Embase, Science Direct, Scopus, Web of Science, and Google Scholar databases were consulted, and PRISMA guidelines were followed in the selection of the studies. In total, 526 articles were found in the databases, and of these, only 28 full texts were eligible for inclusion. After applying the inclusion and exclusion criteria, seven studies were finally included. The results showed that the use of yacon flour can reduce glycemia, HbA1c, advanced glycation ends, plasma lipids, body fat mass, body weight, and waist circumference and improve intestinal microbiota and the antioxidant status. Further exploration of the effects of yacon flour is warranted, and additional clinical trials are necessary to determine the optimal daily consumption levels required to assist in improving metabolic parameters.

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