The genotypes of HCV in the general population of a northern Italian town

Maggi, Giovanni; Armitano, S.; Cairó, Mireia; Galvani, Guilherme David; Gola, Deepak; Marmondi, E.; Passarella, S.; Posca, M.; Vegezzi, P. G.; Vergani, Carlo; Leo, Giulio De

doi:10.1016/s0168-8278(98)80932-x

Cited by 1 publication

(2 citation statements)

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“…The improvement of sterilization procedures and safer practices have probably contributed to the current reduction of HCV outbreaks. Serological surveys in the general population carried out in European countries show a similar age-related distribution of anti-HCV prevalence, suggesting similar modes of HCV transmission [ Stroffolini et al, 1995;Dubois et al, 1997;Guadagnino et al, 1997;Maggi et al, 1997;Osella et al, 1997;Palitsch et al, 1999]. A similar study in the United States, however, showed a different age-related distribution.…”

Section: Discussionmentioning

confidence: 95%

“…A comparison of anti-HCV prevalences in the general population found in seroepidemiological surveys carried out in Europe shows a north to south gradient, in parallel with the level of socioeconomic development. The lowest prevalences were found in the normal Flemish population (0.87%) [Beutels et al, 1997], in Germany (0.63%) [Palitsch et al, 1999] and in France (1.15%) [Dubois et al, 1997], intermediate prevalences in Spain (2% and 2.5%) [Sacristan et al, 1996] and higher prevalences in Italy (5% in the North, 8.4% in Central Italy and 12.6% in the South) [Stroffolini et al, 1995;Maggi et al, 1997;Osella et al, 1997].…”

Section: Discussionmentioning

confidence: 99%

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Community‐based seroepidemiological survey of HCV infection in Catalonia, Spain

Domı́nguez¹,

Bruguera

Vidal

et al. 2001

Journal of Medical Virology

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The objective of this study was to investigate the prevalence of antibodies against the hepatitis C virus (anti-HCV) and the associated risk factors in a representative sample of the population of Catalonia, Spain. Serum samples from 2,142 subjects aged between 5 and 70 years, selected at random from urban and rural habitats, were studied. Multiple logistic regression analysis was carried out to determine variables associated independently with the presence of HCV antibodies. The age and gender standardized prevalence of anti-HCV was 2.5% (95% confidence interval, 1.8-3.2). Prevalence increased significantly with age (P < 0.001), but no other sociodemographic variables were associated with HCV infection. Tattoos (OR: 6.2), blood transfusions (OR: 5.0) intravenous drug use (OR: 4.9) and antecedents of hospitalization (OR: 2.3) were variables associated independently with infection. HCV infection affects mainly elderly people in Spain and spares children and adolescents. This suggests that major exposure to HCV may have occurred many years ago, when infection was more widespread than in recent years.

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