The Genotype—Phenotype Conundrum for Antimicrobial Susceptibility Testing

Novel Clinical mNGS-Based Machine Learning Model for Rapid Antimicrobial Susceptibility Testing of Acinetobacter baumannii

“…The exploration of rapid antimicrobial susceptibility testing (AST) based on molecular methods represents an attractive approach for the early detection of MDR bacteria. However, due to differences in genotype and phenotype, determining exactly how to use molecular data to generate accurate AST results has been difficult for scientists ( 2 , 3 ). Here, we utilized a rapid AST prediction model to obtain accurate antimicrobial susceptibility results, and this model was successfully applied to Acinetobacter baumannii .…”