The genomic characteristics affect phenotypic diversity from the perspective of genetic improvement of economic traits

Research progress and applications of genome‐wide association study in farm animals

“…Over a decade of improvements in sequencing technology, whole-genome sequencing and modified reduced genome sequencing (e.g., RAD, RRGS, and GBS) have occurred and SNPs are the most common markers in recent studies [89][90][91]. Currently, multiple genomic variant types, including copy number variations (CNVs) [92][93][94], insertion-deletion (InDel) [84,95], structure variations (SV) [96][97][98], haplotype [99], presence/absence variations (PAVs) based on pan-genome [100], and even epigenomic markers [101] have gained increasing attention through GWAS. Multiple variant profiles have been generated for multiple breeds [102,103].…”

Comparative population genomics analysis uncovers genomic footprints and genes influencing body weight trait in Chinese indigenous chicken

“…MTM1 and SFPR2 genes can be considered as potential candidate gene for body size-related traits in Asian Game type chickens and Asian Bantam breeds ( Lyu et al, 2023 ). SOX5, IGF1 , and MYH1A, MYH1B , and MYH1D genes have been associated with growth and body weight in commercial broilers and Jinghong layer ( Tan et al, 2022 ; Chu, 2023 ). Despite these achievements, most studies have largely focused on either commercial breeds or specific local populations, and most have been performed with genomic data from limited indigenous chicken breeds, the number of QTL loci is limited.…”