The genetic legacy of the Hunyadi descendants

Neparáczki, Endre; Kis, Luca; Maróti, Zoltán; Kovacs, Beatrix; Varga, Gergely I. B.; Makoldi, Miklós; Pamjav, Horolma; Teiszler, Éva; Tihanyi, Balázs; Nagy, Péter L.; Maár, K; Gyenesei, Attila; Schütz, Oszkár; Dudás, Eszter; Török, Tibor; Pascuttini-Juraga, Vesna; Peharda, Ivančica; Vizi, László Tamás; Horváth-Lugossy, Gábor; Kásler, Miklós

doi:10.1016/j.heliyon.2022.e11731

Cited by 5 publications

(5 citation statements)

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“…We identified shared IBD segments longer that 8cM between the Abasár genomes and those of the Huns, Avars and conquering Hungarians published by ( 32 ). We also tested IBD sharing with the additional medieval samples from Hungary, as the Pericei genomes ( 5 ) the Corvinus ( 4 ) and the Árpáds ( 8 ). In the IBD graph of Figure 6, we illustrated all detected IBD connections between the samples from Abasár and other samples with a minimum cumulative IBD length of 10 cM.…”

Section: Resultsmentioning

confidence: 99%

“…Importantly, based on shared IBDs, these families exhibit distant connections to medieval and early modern Hungarian noble lineages, including the Corvins ( 4 ) and the Báthorys ( 5 ). The shared IBDs between some Abasár samples and members of the Árpád dynasty align with historical records, which document at least one marriage between the two families.…”

Section: Resultsmentioning

confidence: 99%

“…Such combined methods enabled the identification of Richard III's skeleton (1), the remains of Romanov family members (2), or Birger Magnusson, the founder of Stockholm (3). This approach was also the key to identify the famous Hungarian king, Matthias Corvinus' descendants (4), or the members of the Báthory family, one of the most prominent aristocratic families of Medieval Central Europe (5). Archaeogenetic methods have also facilitated the identification of members of the Árpád dynasty, Hungary's first royal family, and to analyse their genomic heritage (6)(7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

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Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary

Varga,

Maróti,

Schütz

et al. 2024

Preprint

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The Aba family played a pivotal role in the early history of Medieval Hungary dominating extensive territories and giving rise to influential figures. We conducted an archaeogenetic examination of remains uncovered at the necropolis in Abasar, the political centre of the Aba clan, to identify Aba family members and shed light on their genetic origins. Utilizing Whole Genome Sequencing (WGS) data from 19 individuals, complemented by radiocarbon measurements, we identified 6 members of the Aba family who shared close kinship relations. Our analysis revealed that 4 males from this family carried identical N1a1a1a1a4~ haplogroups. Significantly, our phylogenetic investigation traced this royal paternal lineage back to Mongolia, strongly suggesting its migration to the Carpathian Basin with the conquering Hungarians. Genome analysis, incorporating ADMIXTURE, Principal Component Analysis (PCA), and qpAdm, revealed East Eurasian patterns in the studied genomes, consistent with our phylogenetic results. Shared Identity by Descent (IBD) analysis confirmed the family kinship relations and shed light on further external kinship connections. It revealed that members of the Aba family were related to members of prominent Hungarian medieval noble families the Arpads, Bathorys and Corvinus as well as to the first-generation immigrant elite of the Hungarian conquest.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary

Varga,

Maróti,

Schütz

et al. 2024

Preprint

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“…Bár maga a laboratóriumi technológia az archeogenetikai kutatásokban az alapjait tekintve változatlan maradt, a szekvenálás áteresztőképessége, illetve a számítástechnikai módszertan a következő, csaknem egy évtizedben is hatalmas fejlődésen ment át. Az újgenerációs technológiával készült önálló hazai kutatások kezdetben elsősorban még mindig a mitokondrium -ezúttal már teljes -DNS-állományát célozták (Csáky et al, 2020a;2020b;Neparáczki et al, 2017;, ezt a 2020-as évektől a kutatócsoportok átszervezését követően -Szegeden az egyetemi laboratórium és a Magyarságkutató Intézet összefonódva, Török Tibor és Neparáczki Endre vezetésével, Budapesten pedig a Bölcsészettudományi Kutatóközpont önálló intézeteként (Archeogenomikai Intézet, AGI) Szécsényi-Nagy Anna vezetésével -egyre gyakrabban a már teljes sejtmagi genomot vizsgáló publikációk követték (Gerber et al, 2023;Maróti et al, 2022;Neparáczki et al, 2022;Varga et al, 2022). Mindezek mellett számos külföldi együttműködésben zajló kutatás is napirenden van, ezek között szerepelt az európai neolitikum humán populációinak genetikai vizsgálata (Lipson et al, 2017), a harangedényes kultúrához tartozó népcsoportok vizsgálata (Olalde et al, 2018), a háziasított lovak eredetének feltárása (Librado et al, 2021), illetve későbbi korból, III.…”

Section: A Magyarországi Archeogenomikai Kutatások Technológiai Fejlő...unclassified

Az archeogenomikai vizsgálatok múltja, jelene és jövője Magyarországon

Gerber

2023

Késő Rézkori Temetkezések Régészeti És Bioarcheológiai Elemzése

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“…The raw data of the medieval dataset can be accessed at European Nucleotide Archive ( http://www.ebi.ac.uk/ena ) under the accession number PRJEB47418 [ 42 ]. We deposited the medieval dataset and the subset of 1KG Phase III individuals presented in this manuscript at in PLINK 1240K binary format [ 34 ].…”

mentioning

confidence: 99%

correctKin: an optimized method to infer relatedness up to the 4th degree from low-coverage ancient human genomes

et al. 2023

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Kinship analysis from very low-coverage ancient sequences has been possible up to the second degree with large uncertainties. We propose a new, accurate, and fast method, correctKin, to estimate the kinship coefficient and the confidence interval using low-coverage ancient data. We perform simulations and also validate correctKin on experimental modern and ancient data with widely different genome coverages (0.12×–11.9×) using samples with known family relations and known/unknown population structure. Based on our results, correctKin allows for the reliable identification of relatedness up to the 4th degree from variable/low-coverage ancient or badly degraded forensic whole genome sequencing data.

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The genetic legacy of the Hunyadi descendants

Cited by 5 publications

References 43 publications

Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary

Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary

Az archeogenomikai vizsgálatok múltja, jelene és jövője Magyarországon

correctKin: an optimized method to infer relatedness up to the 4th degree from low-coverage ancient human genomes

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