The genetic landscape of autism spectrum disorder in the Middle Eastern population
Yasser Al-Sarraj,
Rowaida Z. Taha,
Eman Al-Dous
et al.
Abstract:Introduction: Autism spectrum disorder (ASD) is characterized by aberrations in social interaction and communication associated with repetitive behaviors and interests, with strong clinical heterogeneity. Genetic factors play an important role in ASD, but about 75% of ASD cases have an undetermined genetic risk.Methods: We extensively investigated an ASD cohort made of 102 families from the Middle Eastern population of Qatar. First, we investigated the copy number variations (CNV) contribution using genome-wid… Show more
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