-We studied the hormonal and psychological effect of the full shift rota on junior doctors after implementation of the European Working Time Directive, using a comparative, crosssectional study design of male doctors in South Yorkshire. Cortisol and testosterone levels were measured and subjects completed the general health questionnaire (GHQ-12) and the androgen deficiency in the aging male screening questionnaire (ADAM), after a week of holiday (baseline), a week of nights, and a normal working week. The results showed that cortisol levels decreased from 480.6±33.1 nmol/l at baseline (after a week of holiday), to 355.7±29.1 nmol/l post normal working week (p=0.003); to 396.7±32.5 nmol/l post nights (p=0.03). GHQ-12 scores increased from 0.5±0.3 at baseline, to 1.8±0.5 post normal working week (p=0.02) and to 2.3±0.5 post nights (p=0.005). These results suggest that there are still appreciable physiological consequences with new work patterns.
KEY WORDS: hormones, junior physician, psychology ObjectivesHistorically junior doctors' training involved long working hours with little sleep overnight 1 and was recognized to be hazardous to both the doctor's and patient's health. [1][2][3] The association between long working hours and illness occurs largely as a result of stress, as doctors try to maintain performance levels with increasing fatigue. 4 Stress results in emotional, behavioral and psychological reactions, 5 such as anxiety, depression, increased consumption of alcohol, increased blood pressure and, in extreme cases, death, through suicide or cardiovascular disease. There is evidence that shift work is associated with an increased risk of cardiovascular disease 6 and gastrointestinal disorders, 7 which are thought to be due to alterations in the circadian rhythm, following changes to the sleep-wake cycle. 8 Circadian adjustment takes time, being most rapid in the first 1-3 days 9 and during this period the subject experiences jet lag or desynchronosis. The most important consequence is reduced quantity and quality of sleep, 8,9 which has been linked to declines in both cognitive and psychomotor performance in junior doctors. 1 Human error is also more common during the night, as shown in the increase in single vehicle car crashes, due to drivers falling asleep at the wheel and driving off the road, which peak between 1 and 4am. 10 The effect of stress and shift work in doctors was first measured in 1971, 1 in a study of reporting errors on electrocardiographs. More recent studies have shown increased attentional failures 2 and an increase in serious medical errors 3 when doctors work frequent 24-hour shifts, as compared with shifts of a maximum 16 hours and reduced total hours worked per week.The evidence on the adverse effects of stress, long working hours and sleep deprivation in doctors led to the Government, doctor's representatives and NHS managers to agree the 'New Deal' in 1991. This improved junior doctors working conditions, by ensuring that the maximum contracted hours for a full shift...