The Gate Theory of Pain Revisited: Modeling Different Pain Conditions with a Parsimonious Neurocomputational Model

Peláez, Francisco Javier Ropero; Taniguchi, S.

doi:10.1155/2016/4131395

Cited by 35 publications

(19 citation statements)

References 20 publications

(24 reference statements)

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“…The adult analog is rubbing a bumped “crazy bone”. In a study called “The Gate Theory of Pain Revisited”, a neurocomputational model was formulated that was consistent with the biological one in that pain signals to the brain were blocked when the same area that was “pained” was touched [57]. Stimulation of pressure receptors results in increased vagal activity and serotonin levels (the body’s natural pain suppressor) [58].…”

Section: Child and Adolescent Massage Therapymentioning

confidence: 99%

Pediatric Massage Therapy Research: A Narrative Review

Field

2019

Children

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This narrative review on pediatric massage literature from the last decade suggests that massage therapy has positive effects on several pediatric conditions. These include preterm infant growth, psychological problems including aggression, gastrointestinal problems including constipation and diarrhea, painful conditions including burns and sickle cell, muscle tone disorders including cerebral palsy and Down syndrome, and chronic illnesses including diabetes, asthma cancer, and HIV. Potential underlying mechanisms for the massage therapy effects include increased vagal activity and decreased stress hormones. Limitations of the literature include the need for more randomized controlled trials, longitudinal studies, and underlying mechanism studies.

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Section: Child and Adolescent Massage Therapymentioning

confidence: 99%

Pediatric Massage Therapy Research: A Narrative Review

Field

2019

Children

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“…The effect of heat to reduce pain is explained by the gate theory of pain. This theory suggests that there is a gate mechanism in the spinal cord that inhibits the crossing of pain signals by closing the gate system in the spinal cord (9). Heat increases pain threshold with increasing temperature, blood circulation, and metabolism and reduces muscle spasms (10).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Localized Heat and Cold Therapy on Pain Intensity, Duration of Phases of Labor, and Birth Outcomes Among Primiparous Females: A Randomized, Controlled Trial

2018

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Background: Pain is a common and unavoidable phenomenon in childbirth, and in terms of severity, childbirth pain is among the most severe pains in human. Objectives: The current study aimed at investigating the effect of localized heat and cold therapy on pain intensity, duration of phases of labor, and birth outcomes among primiparous females. Satisfaction was also compared in the two intervention groups. Methods: The current randomized, controlled trial was conducted on 120 primiparous females in three groups (heat/ cold therapy, and control) from September 2015 to January 2016. Intensity of pain, duration of phases of labor, and birth outcomes were measured before and after intervention in the three groups. Satisfaction with localized heat and cold therapy was compared in the two intervention groups. No intervention was conducted in the control group. Data were analyzed using the Fisher exact, Chi-square, the Kruskal-Wallis, and ANOVA tests with SPSS version 19. Results: After intervention, statistically significant difference was found in the average pain severity respectively among the heat therapy, cold therapy, and control groups in dilations of 5 -6 cm (3.25 ± 0.91, 3.57 ± 1.14, 4.00 ± 1.37) 7 -8 cm (4.08 ± 0.91, 4.88 ± 1.05, 4.97 ± 1.17), and 9 -10 cm (6.00 ± 1.35, 6.40 ± 1.09, 7.80 ± 1.18) in the first and second phase of the labor (6.22 ± 1.13, 7.37 ± 1.08, 7.94 ± 1.08). There was a statistically significant differences in the average duration of first phase of labor, respectively among heat therapy, cold therapy, and control groups (293.70 ± 68.97, 368.57 ± 79.82, 400.86 ± 77.43) and second phases of labor respectively among heat therapy, cold therapy, and control groups (42.85 ± 13.60, 51.71 ± 12.24, 46.85 ± 13.67), but there was no statistically significant difference among the three groups in terms of the average duration of labor in the third phase. No significant difference was observed between heat and cold therapy groups in terms of satisfaction. No significant difference was observed among the three groups in birth outcomes, including the mean first and fifth Apgar scores, time of cuddling newborn, and the first breastfeeding of newborn. Conclusions: Localized heat and cold therapy are non-pharmacological, non-invasive, satisfactory for the primiparous females, and effective methods to control and relieve pain during labor without adverse effects on maternal and fetal outcomes.

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“…The gate control theory by Melzack and Wall in 1965 [ 27 ] is the most widely accepted mechanism for pain relief in ES. This theory was revisited by Taniguchi et al in 2015 and shown to be valid [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Percutaneous tibial nerve stimulation (PTNS): an alternative treatment option for chronic therapy resistant anal fissure

et al. 2019

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Background The aim of the present study was to evaluate percutaneous tibial nerve stimulation (PTNS) for treatment resistant chronic anal fissure. Methods Consecutive patients with chronic anal fissure were treated with neuromodulation via the posterior tibial nerve between October 2013 and January 2014. Patients had PTNS for 30 min on 10 consecutive days. All patients had failed conventional medical treatment. The visual analogue scale (VAS) score, St. Marks score, Wexner’s constipation score, Brief Pain Inventory (BPI-SF), bleeding and mucosal healing were evaluated before treatment, at termination, after 3 months, and then yearly for 3 years. Results Ten patients (4 males and 6 females; mean age 49.8 years) were identified but only 9 were evaluated as one patient’s fissure healed before PTNS was started. At 3-year follow-up, fissures had remained completely healed in 5 out of 9 patients. All patients stopped bleeding and were almost completely pain-free at 3 years (VAS p = 0.010) and pain relief improved from 50% at completion to 90% at 3 years. The patients’ Wexner constipation scores improved significantly ( p = 0.007). Conclusions In this small series, PTNS enhanced healing of chronic anal fissure and reduced pain and bleeding with an associated improvement in bowel function.

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The Gate Theory of Pain Revisited: Modeling Different Pain Conditions with a Parsimonious Neurocomputational Model

Cited by 35 publications

References 20 publications

Pediatric Massage Therapy Research: A Narrative Review

Pediatric Massage Therapy Research: A Narrative Review

The Effect of Localized Heat and Cold Therapy on Pain Intensity, Duration of Phases of Labor, and Birth Outcomes Among Primiparous Females: A Randomized, Controlled Trial

Percutaneous tibial nerve stimulation (PTNS): an alternative treatment option for chronic therapy resistant anal fissure

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