The gastroprotective effects of arrowroot tuber starch (Maranta arundinacea L.) on ethanol-induced gastric damages in rats

Abstract

Empirically, arrowroot tubers (Maranta arundinacea L.) have been widely used in the treatment of gastric ulcers. They are known to contain carbohydrates and flavonoids that play a role in reducing inflammation. This study sought to identify the gastroprotective effects of arrowroot tuber starch (Maranta arundinacea L.) on the ulcer index, % protection ratio, and the histopathological image of Wistar rat models of gastric ulcers. The test animals were divided into six groups. Group I was given free access to food and water (normal control), while Group II was given ethanol without treatment (negative control). Groups III, IV, and V were treated with arrowroot tuber starch at the doses of 125, 250, and 500 mg/kg BW, respectively. Group VI was given sucralfate at the dose of 400 mg/kg BW (positive control). All treatments were administered orally for 14 days and followed by 24 hours of fasting. On Day 15, all groups, except for the normal control, were given 96% ethanol orally at the dose of 1 ml/200gr BW. After one hour, they were dissected, and their stomach was removed for further analyses. The results showed that the administrations of arrowroot tuber starch at 125, 250, and 500 mg/kg BW produced ulcer indices of 2, 1.25, and 1.5, respectively, smaller than the negative control (4.25), and % protection ratios higher than the positive control. The histopathological imaging showed that the stomach of rats receiving arrowroot tuber starch at 250 mg/kg BW presented no pathological changes. Based on these findings, the arrowroot tuber starch is proven to have the ability as a gastroprotective agent.

Wild Edible Plants as an Alternative Food Source for The Community of Pakis Baru Village, Nawangan, Pacitan

“…Jenang garut biasa dikonsumsi masyarakat setempat untuk meredakan sakit perut yang diakibatkan asam lambung (Hasil wawancara: Prihatin, 2024). Hal ini sejalan dengan penelitian Lailli et al (2020) yang menyebutkan bahwa kandungan polisakarida dalam umbi garut dipercaya dapat berikatan dengan area mukosa lambung sehingga mampu meningkatkan kemampuan pati garut dalam membentuk lapisan pelindung pada dindinglambung.…”

Physical and 3D Printing Properties of Arrowroot Starch Gels

“…The arrowroot starches have potential medicinal properties, such as the treatment of gastric ulcers and the protection of the gastrointestinal tract. Damarwati et al (2020) indicated that arrowroot tuber starch could improve rat stomachs after the ulcer induction [ 1 ]. Meanwhile, Gutierrez et al (2018) suggested that arrowroot starches had a low in vitro digestibility rate, which was beneficial for people suffering from obesity and diabetes [ 2 ].…”

“…Rheological properties of starch gels, such as thixotropism, viscoelasticity, solidification rate and temperature response during extrusion, are the most important parameters associated with the accuracy and shelf life of 3D printed products [ 15 , 16 ]. However, the above-mentioned rheological properties of arrowroot starch gels have not been fully investigated before [ 1 ].…”