The gastric blood flow and its distribution by I131-MAA

Asano, K.; Kunisada, Makoto; Yamagata, Akifusa; Nagao, Toshihiro; Hiraki, Kiyoshi; Utsunomiya, T.; Miyake, Hirofumi

doi:10.1007/bf02777842

Cited by 25 publications

(1 citation statement)

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“…Most of the gastric blood flow is distributed to the mucosa; 70,71 thus, monitoring the microcirculation from the mucosal side might give a more representative information of the blood flow redistribution 50,60 . When does this redistribution affect the muscular layers remains unclear?…”

Section: Experimental Models Used For Ischemic Conditioning Of the Stmentioning

confidence: 99%

Vascular conditioning of the stomach before esophageal reconstruction by gastric interposition

Yuan¹,

Duranceau²,

Ferraro³

et al. 2012

Diseases of the Esophagus

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Gastric interposition with intrathoracic or cervical esophagogastrostomy is currently the preferred operation for reconstruction after esophagectomy. Anastomotic leaks however result from poor vascular supply to the proximal stomach. They are responsible for significant morbidity and mortality. 'Ischemic conditioning' of the interposed stomach has been proposed as a technique where the 'delay phenomenon' aims at improving the microcirculation of the gastric conduit and preventing anastomotic leakage. Experimental observations and clinical studies have been conducted to document the immediate effects and results of this approach. The aim of this work is to review the principles, pathophysiology, experimental, and clinical evidence related to vascular conditioning of the stomach prior to esophagectomy with gastric interposition and esophagogastric anastomosis. MEDLINE and PubMed were searched to identify articles related to vascular conditioning of the stomach. Cross references were added and reviewed to complete the reference list. The anatomic basis of ischemic conditioning, the prevalence of ischemic events on the gastric conduit, the methodology to assess the microcirculation before and after gastric devascularization, animal experiments, and clinical studies reported on this approach were reviewed. Ten experimental works, eleven clinical observations, four reviews, and two editorial commentaries addressing ischemic conditioning of the stomach were identified and reviewed. Experimental observations document improved microcirculation to the proximal stomach following partial gastric devascularization. Clinical reports show the feasibility and relative safety of gastric ischemic conditioning. Preliminary observations suggest potential improvements to the gastric microcirculation resulting from gastric ischemic conditioning. This approach may help prevent complications at the esophagogastric anastomosis. The actual level of evidence however cannot promote its use outside of clinical research protocols.

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Section: Experimental Models Used For Ischemic Conditioning Of the Stmentioning

confidence: 99%

Vascular conditioning of the stomach before esophageal reconstruction by gastric interposition

Yuan¹,

Duranceau²,

Ferraro³

et al. 2012

Diseases of the Esophagus

View full text Add to dashboard Cite

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Production, purification, characterization, immobilization, and application of β‐galactosidase: a review

Nath

Mondal

Chakraborty

et al. 2014

Asia-Pacific J Chem Eng

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Biopharmaceuticals are new categorizing biomolecules, which are the results of incredible proliferation in the field of biotechnology. One of the challenging biomolecule β-galactosidase (β-galactosidase galacto hydrolysase, trivially lactase) catalyzes hydrolysis of lactose to produce glucose and galactose, and in some cases, it takes part in transgalactosylation reaction that produces functional food galato-oligosaccharide. A wide variety of strategies had been already attempted for production of β-galactosidase through fermentative route. Beside the upstream process, downstream technology towards purification and immobilization of target enzyme also create great attentions. Subsequently, its wide applications in the field of food, biopharmaceuticals, dairy, diagnosis, and waste treatment boost up biotechnological economy as well as zero-effluent discharge. In dairy industry, β-galactosidase has been used to degrade lactose, prevent crystallization of lactose, improve sweetness, and increase the solubility of milk product, otherwise which would be an environmental pollutant. In food and pharmaceutical industries, β-galactosidase has been used to prepare low lactosecontaining food products for low lactose-tolerant people. Therefore, it is obvious to elucidate different technological aspects of β-galactosidase, which may provide a great knowledge in educational and industrial field. Taking the enzyme into account, a ready review has been made about its production, purification, characterization, and immobilization technology. The review also addresses wide applications of β-galactosidase in different fields.

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Genetics of Lactose Digestion in Humans

Flatz

1987

Advances in Human Genetics

106

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The gastric blood flow and its distribution by I131-MAA

Cited by 25 publications

References 0 publications

Vascular conditioning of the stomach before esophageal reconstruction by gastric interposition

Vascular conditioning of the stomach before esophageal reconstruction by gastric interposition

Production, purification, characterization, immobilization, and application of β‐galactosidase: a review

Genetics of Lactose Digestion in Humans

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