“…In the first study, the lectin extracted from the seeds of Dioclea violet (DVL) was evaluated, and although it did not present any clinical activity when evaluated alone (MIC ≥ 1024 μg/mL), DVL–gentamicin combination increased the antibiotic activity expressively, reducing the gentamicin MIC from 50.8 to 10.1 μg/mL against MDR S. aureus , and from 32 to 12.7 μg/mL against MDR E. coli [ 56 ]. In the second study, similar results were observed when Santos et al [ 57 ] evaluated the lectin extracted from Vatairea macrocarpa (VML) seeds (MIC ≥ 1024 μg/mL); furthermore, when combined with gentamicin, norfloxacin, and penicillin, an increase in antibiotic activity was also seen, with an MIC reduction of 512 to 128 μg/mL, 40.3 to 32 μg/mL, and 512 to 406.4 μg/mL, respectively, against MDR S. aureus [ 57 ].…”