“…However, depending on the type of bioactive compound administered, its effectiveness may be limited because of instability or the body's recognition of xenobiotic substances, raising concerns about the occurrence of unforeseen side effects [160]. One approach to solving such problems is to use a drug delivery system [186]. Drug delivery systems encapsulate bioactive components in formulated health materials such as liposomes and nanoparticles.…”
Section: Materials For Light-activated Liposomesmentioning
Aging increases oxidative and inflammatory stress caused by a reduction in metabolism and clearance, thus leading to the development of age-associated diseases. The quality of our daily diet and exercise is important for the prevention of these diseases. Marine resources contain various valuable nutrients, and unique glycerophospholipid plasmalogens are found abundantly in some marine invertebrates, including ascidians. One of the major classes, the ethanolamine class (PlsEtn), exists in a high ratio to phospholipids in the brain and blood, while decreased levels have been reported in patients with age-associated diseases, including Alzheimer’s disease. Animal studies have shown that the administration of marine PlsEtn prepared from marine invertebrates improved PlsEtn levels in the body and alleviated inflammation. Animal and human studies have reported that marine PlsEtn ameliorates cognitive impairment. In this review, we highlight the biological significance, relationships with age-associated diseases, food functions, and healthcare materials of plasmalogens based on recent knowledge and discuss the contribution of marine plasmalogens to health maintenance in aging.
“…However, depending on the type of bioactive compound administered, its effectiveness may be limited because of instability or the body's recognition of xenobiotic substances, raising concerns about the occurrence of unforeseen side effects [160]. One approach to solving such problems is to use a drug delivery system [186]. Drug delivery systems encapsulate bioactive components in formulated health materials such as liposomes and nanoparticles.…”
Section: Materials For Light-activated Liposomesmentioning
Aging increases oxidative and inflammatory stress caused by a reduction in metabolism and clearance, thus leading to the development of age-associated diseases. The quality of our daily diet and exercise is important for the prevention of these diseases. Marine resources contain various valuable nutrients, and unique glycerophospholipid plasmalogens are found abundantly in some marine invertebrates, including ascidians. One of the major classes, the ethanolamine class (PlsEtn), exists in a high ratio to phospholipids in the brain and blood, while decreased levels have been reported in patients with age-associated diseases, including Alzheimer’s disease. Animal studies have shown that the administration of marine PlsEtn prepared from marine invertebrates improved PlsEtn levels in the body and alleviated inflammation. Animal and human studies have reported that marine PlsEtn ameliorates cognitive impairment. In this review, we highlight the biological significance, relationships with age-associated diseases, food functions, and healthcare materials of plasmalogens based on recent knowledge and discuss the contribution of marine plasmalogens to health maintenance in aging.
“…Before joining SJTU, she earned her Ph.D. degree in Chemical and Biomolecular Engineering at the Korea Advanced Institute of Science & Technology (KAIST) in 2009 and then worked as a postdoctoral researcher at Tufts University. In 2020, she coauthored a manuscript in Chemistry of Materials on dynamic functional hydrogels, which was recently highlighted in our Virtual Issue on The Future of Healthcare Materials . Like Stucky and Chebanov, Xia is also greatly inspired by nature but directs that inspiration in different directions as shared herein.…”
Section: Xiao-xia Xiamentioning
confidence: 99%
“…In 2020, she coauthored a manuscript in Chemistry of Materials on dynamic functional hydrogels, 4 which was recently highlighted in our Virtual Issue on The Future of Healthcare Materials. 5 Like Stucky and Chebanov, Xia is also greatly inspired by nature but directs that inspiration in different directions as shared herein.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.