The future of cancer therapy: exploring the potential of patient-derived organoids in drug development
Cigir Biray Avci,
Bakiye Goker Bagca,
Behrouz Shademan
et al.
Abstract:Cancer therapy is on the brink of a significant transformation with the inclusion of patient-derived organoids (PDOs) in drug development. These three-dimensional cell cultures, directly derived from a patient’s tumor, accurately replicate the complex structure and genetic makeup of the original cancer. This makes them a promising tool for advancing oncology. In this review, we explore the practical applications of PDOs in clinical drug screening and pharmacognostic assessment, as well as their role in refinin… Show more
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