2021
DOI: 10.1016/j.trsl.2020.11.011
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The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats

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Cited by 11 publications
(29 citation statements)
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“…the tubular functional reserve). In agreement with this, as we showed previously, [21] the FST is a very sensitive but low-resolution tubule injury test. Accordingly, the FST is very useful for detecting subtle alterations, but additional biomarkers are needed to inform damage granularity.…”
Section: Discussionsupporting
confidence: 92%
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“…the tubular functional reserve). In agreement with this, as we showed previously, [21] the FST is a very sensitive but low-resolution tubule injury test. Accordingly, the FST is very useful for detecting subtle alterations, but additional biomarkers are needed to inform damage granularity.…”
Section: Discussionsupporting
confidence: 92%
“…no damage takes place) showed reduced furosemideinduced diuresis and K + excretion. [21] In the present study, we observed that, during two weeks after overt damage has occurred, the urine output and K + urinary excretion forced by furosemide are also signi cantly reduced, thus denoting that there are still alterations in tubular function that mostly affect its response capacity (i.e. the tubular functional reserve).…”
Section: Discussionsupporting
confidence: 46%
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