Abstract.Suppose G acts effectively as a group of homeomorphisms of the connected, locally path connected, simply connected, locally compact metric space X. Let G denote the closure of G in Homeo^), and N the smallest normal subgroup of G which contains the path component of the identity of G and all those elements of G which have fixed points. We show that irx(X/G) is isomorphic to G/N subject to a weak path lifting assumption for the projection X -* X/G.Given a topological space X together with a group G of homeomorphisms of X, what can we say about the fundamental group of the orbit space X/G! Results for simplicial and discontinuous groups have been given in [1] and [2]. The object of this note is to produce a theorem which can deal with both discontinuous and continuous actions.We shall assume that A' is a connected, locally path connected, locally compact metric space. Let G be a group of homeomorphisms of X which acts effectively on X, so that we can think of G as a subgroup of the group Homeo(Ar) of all homeomorphisms of X endowed with the compact open topology.Under very reasonable hypotheses (see conditions A,B,C below) the answer to our question is as follows. Let G denote the closure of G in Homeo(Ar), and let N be the smallest normal subgroup of G which contains the path component of the identity of G and all those elements of G which have fixed points. Then if A' is simply connected the fundamental group of X/G is isomorphic to the quotient group G/N.Suppose X fails to be simply connected but has a universal covering space X. Each homeomorphism g: X -» X lifts to a homeomorphism of X, and any two lifts of the same g differ by a covering transformation. Therefore we have an action of an extension of itx(X) by G on X whose orbit space is homeomorphic to X/G, and we can apply our result in this setting. Details of the group extension and of its action on X can be found in [5] and [3].Here are some examples to illustrate a variety of situations in which the result can be used. Example 1. Take S2 X R for X and Sx X Z for G, the action being as follows.The circle acts on S2 by rotation leaving the north and south poles fixed, and acts trivially on R. The generator of Z reflects S2 in the equator and translates R along