Abstract:Background: Parkinson's disease (PD) is often associated with cognitive impairment. However, the neural mechanism of cognitive impairment is not clear. The present study investigated the functional and anatomic changes in PD patients with mild cognitive impairment (MCI) and their correlations with cognitive functions by the application of combined functional and structural analysis. Methods: T1-weighted magnetic resonance imaging (MRI) and resting-state functional MRI data were acquired from 23 PD patients wit… Show more
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