2018
DOI: 10.1097/prs.0000000000004364
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The Functional Anatomy of the Superficial Fat Compartments of the Face: A Detailed Imaging Study

Abstract: This study confirms the presence of distinct subcutaneous fat compartments and provides evidence for an individual behavior when soft-tissue fillers are applied: inferior displacement of the superficial nasolabial, middle cheek, and jowl compartments, in contrast to an increase in volume without displacement (i.e., an increase in projection) of the medial cheek, lateral cheek, and both superficial temporal compartments.

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Cited by 98 publications
(108 citation statements)
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References 23 publications
(46 reference statements)
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“…The superficial fat volume of the infraorbital and perioral regions was significantly greater at the lower than the upper area, which confirms the trends found in previous studies (Gierloff et al, ; Schenck et al, ; Wysong et al, ). Based on these results, it is better to consider this area for volume restoration using filler, since the superficial fat volume of the upper area of the infraorbital region can naturally reduce with age.…”
Section: Discussionsupporting
confidence: 91%
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“…The superficial fat volume of the infraorbital and perioral regions was significantly greater at the lower than the upper area, which confirms the trends found in previous studies (Gierloff et al, ; Schenck et al, ; Wysong et al, ). Based on these results, it is better to consider this area for volume restoration using filler, since the superficial fat volume of the upper area of the infraorbital region can naturally reduce with age.…”
Section: Discussionsupporting
confidence: 91%
“…In‐depth morphological studies of the human body have been performed using various diagnostic imaging devices. Previous studies that have employed MRI have encountered difficulties in providing in‐depth data for the main anatomical structures of the face because of poor image resolution due to spatial limitations of the head coil (Schenck et al, ). The histology method is limited by soft tissue deformation during tissue processing (Chopra et al, ).…”
Section: Discussionmentioning
confidence: 99%
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“…The boundaries between these different types play a crucial role in the formation of the above‐mentioned age‐related clinical manifestations . Another important shift in paradigms occurred after the introduction of the 5 Layers of the face: Layer 1: Skin, Layer 2: Subcutaneous fat including retinacula cutis (composed of fibrous connective tissue), Layer 3: Superficial musculo‐aponeurotic system (SMAS), Layer 4: Deep fat, and Layer 5: Periosteum or deep fascia . This layered arrangement of the face provides anatomic guidance for the identification of discrete anatomic structures, thereby increasing the safety of minimally invasive applications and/or enabling the surgeon to target desired structures for the best esthetic outcomes.…”
Section: Introductionmentioning
confidence: 99%
“…5 Another important shift in paradigms occurred after the introduction of the 5 Layers of the face: Periosteum or deep fascia. 6 This layered arrangement of the face provides anatomic guidance for the identification of discrete anatomic structures, thereby increasing the safety of minimally invasive applications and/or enabling the surgeon to target desired structures for the best esthetic outcomes.…”
Section: Introductionmentioning
confidence: 99%