The frequency of pregnancy and exposure to cytomegalovirus infections among women with a young child in day care

Abstract

OBJECTIVE-To determine the frequency of pregnancy and exposure to CMV among mothers contemplating a possible additional pregnancy and with a child less than 2 years of age in group day care.STUDY DESIGN-We performed a prospective observational study which included a demographic questionnaire and serologic and virologic monitoring of mothers and their children in day care.RESULTS-Of 60 women, 62% were seronegative and 20% had a child shedding CMV. Of the 60 women, 23 women or 38% (95% CI = 0.27, 0.51) became pregnant on average 10 months after enrollment. During pregnancy, eight or 35% (95% CI = 0.19, 0.55) of these pregnant women had a child in day care who shed CMV CONCLUSIONS-These results illustrate the potential magnitude of the public problem associated with exposure to a silent viral infection during pregnancy. Our data, when extrapolated to the U.S. population, estimate that every two years between 31,000 and 168,000 susceptible pregnant women will be exposed to CMV by an infected child.

On the Possibilities of Laboratory Verification of Cytomegalovirus Infection in Children

“…Доказано, что у организо-ванных детей частота выявления вируса достоверно выше по сравнению с детьми, не посещающими ор-ганизованные коллективы [12].…”

Citomegalovirus: De La Infección Neonatal a Las Infecciones en Pacientes Trasplantados Y De La Citomegalia a La Biología Molecular

“…La infección por leche materna no produce los efectos mórbidos de la transmisión congénita, sin embargo sí tiene efectos epidemiológicos, ya que 50% de los niños amamantados por madres seropositivas adquieren la infección al año de edad y mantienen la excreción del virus por meses y años, infectando a otros niños y adultos. La tasa de excreción del virus en guarderías para niños entre 1 y 3 años de edad es cercana al 70% (57,58) .…”

Screening for cytomegalovirus during pregnancy

“…To estimate the frequency of pregnancy and exposure to CMV among mothers contemplating a possible additional pregnancy and with a child less than 2 years of age in group daycare, we recently performed a prospective study which included a demographic questionnaire and serologic and virologic monitoring of mothers and their children in daycare [33]. Of 60 women, 62% were seronegative and 20% of seronegative women had a child shedding CMV.…”