The frequency-doubled Nd-YAG laser with automatic scanning in the treatment of port-wine stains: A preliminary report

Laffitte, F; Mordon, Serge; Chavoin, J.-P.; Bonafé, J. L.; Rougé, Daniel; Costagliola, M

doi:10.1007/bf02594071

Cited by 11 publications

(2 citation statements)

References 10 publications

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“…The frequency doubled Nd:YAG laser has been used in the treatment of port wine stains (Laffitte et al 1992) and treatment effects similar to the ones obtained using the argon ion laser have been reported (Apfelberg et al 1986), suggesting non-specific diffuse dermal coagulation (Neumann et al 1991). The clinical findings are in agreement with our theoretical results in that damage selective to vessels is not attainable with the frequency doubled Nd:YAG laser (table 4).…”

Section: Continuous Wave Laserssupporting

confidence: 87%

Mathematical modelling of dynamic cooling and pre-heating, used to increase the depth of selective damage to blood vessels in laser treatment of port wine stains

Sturesson

Andersson‐Engels

1996

Phys. Med. Biol.

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Abstract. Based on the assumption that the maximum irradiance allowed during laser treatment of port wine stains is limited by the temperature rise at the dermoepidermal junction, we theoretically investigated how much the irradiance could be increased by dynamically cooling the skin surface. The heat condution equation was solved numerically in cylindrical coordinates using a skin model composed of four layers. The laser-light absorption was calculated using Monte Carlo simulations. The transient thermal behaviour of the skin was modelled when cooling with water at a temperature of 0 • C and with liquid nitrogen at a temperature of −196 • C. With cooling, an increase in the maximum irradiance by a factor of 2.3-3.6 was theoretically permitted depending on the irradiation time, wavelength and mode of cooling. The corresponding increase in vessel selective damage depth was predicted to be 0.4-0.5 mm.A new concept for increasing the depth of vessel selective damage is introduced where the initial temperature profile of the skin is reshaped by using not only surface cooling but also laser irradiation. By pre-irradiating the skin with near-infrared light without selective absorption by the tissue chromophores in conjunction with surface cooling, a maximum temperature at a depth of 1 mm from the dermoepidermal junction was theoretically achieved. A subsequent 0.1 s pulse from a frequency doubled Nd:YAG laser is theoretically shown to selectively destroy vessels up to a depth of 0.8 mm from the dermoepidermal junction. By pre-heating at 1064 nm and treating at 532 nm in conjunction with surface cooling, the theoretical results indicate that the Nd:YAG laser can compete in effectiveness with the flashlamp-pumped dye laser in the treatment of port wine stains.

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Section: Continuous Wave Laserssupporting

confidence: 87%

Mathematical modelling of dynamic cooling and pre-heating, used to increase the depth of selective damage to blood vessels in laser treatment of port wine stains

Sturesson

Andersson‐Engels

1996

Phys. Med. Biol.

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“…To treat a large surface area, scanners using reflectors on a two-axial system guided by a processor controlled pattern have been developed. Treatments using an automatic scanner such as the CC scan (Chambers et al 1990) and the multiscan (Laffitte et al 1992) have been achieved to produce more uniform laser dosage than manual techniques can accomplish. For the selective treatment of vascular lesions an automatic scanner called 'Scanall' has been developed.…”

Section: Introductionmentioning

confidence: 99%

Real time control of the spatial selectivity during laser treatment of a biological surface

Gassem¹,

Farcy²,

Pruvost³

2004

Phys. Med. Biol.

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We propose a new irradiation technique to improve the spatial selectivity and the dose control during a laser treatment of a biological surface. The technique is based on the use of a spatial light modulator to project a rectangular laser image of 8 mm x 5 mm. The spatial distribution of the irradiation is controlled in real time by image analysis applied to the acquired image of the surface to be treated. The aim is to discriminate between the target areas to be irradiated and the surrounding parts to be preserved. The resolution is about 12 microm and is limited by the resolution of the camera and the spatial light modulator. For treatments of a large surface we use an intensity correlator to measure the displacement and to avoid an unwanted second irradiation on a target.

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Rationale for automatic scanners in laser treatment of port wine stains

Mordon

Rotteleur²,

Brunetaud³

et al. 1993

Lasers Surg Med

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Laser therapy of port wine stains (PWS) is well established. However, the application of lasers to PWS treatment over the last decade has resulted in the use of many laser systems. The goal of this study is to describe the different laser parameters, treatment techniques, and delivery systems. Two methods, coagulation and microvaporization, are used to destroy the abnormal blood vessels. The coagulation method results in excellent treatment, but it requires careful control of laser parameters during the treatment process. Scanning devices can be utilized for this purpose. The microvaporization method, obtained with a pulsed dye laser, is restricted to PWS composed of small vessels since it is difficult to obtain a pulse longer than 450 microseconds. In addition, numerous retreatments are needed with the pulsed dye method. The initial assessment of the patient should contribute to an improvement in the choice of laser parameters and the outcome of treatment.

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The frequency-doubled Nd-YAG laser with automatic scanning in the treatment of port-wine stains: A preliminary report

Cited by 11 publications

References 10 publications

Mathematical modelling of dynamic cooling and pre-heating, used to increase the depth of selective damage to blood vessels in laser treatment of port wine stains

Mathematical modelling of dynamic cooling and pre-heating, used to increase the depth of selective damage to blood vessels in laser treatment of port wine stains

Real time control of the spatial selectivity during laser treatment of a biological surface

Rationale for automatic scanners in laser treatment of port wine stains

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