The French heritage in clinical kidney transplantation

Starzl, Thomas E.

doi:10.1016/s0955-470x(05)80040-0

Cited by 7 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Pediatric kidney transplant is a relatively young field and has improved the lives of many children with ESKD. Since the first procedure, performed by Louis Michon in 1952, better immunosuppression has prolonged graft survival; however, more can be done to improve survival beyond the first year post‐kidney transplant . RRT in the form of chronic dialysis became available in the 1960s as a bridge to transplantation for children with ESKD, provided children have access to this care.…”

Section: Introductionmentioning

confidence: 99%

Contemporary outcomes of the pediatric kidney transplant program in Johannesburg, South Africa, between 2004 and 2017: Better or not—And which way forward?

Mshumpela

Loveland

Botha

et al. 2020

Pediatric Transplantation

View full text Add to dashboard Cite

Background Outcomes for the pediatric kidney transplant program in Johannesburg (1984‐2003) were found to be suboptimal. In this study, we compared (a) early (era 1:1984‐2003) to contemporary (era 2:2004‐2017) outcomes and (b) compared contemporary outcomes between the public and private sector hospitals in our program. Methods We conducted a retrospective record review of all pediatric (<18 years) KA transplants performed in our kidney transplant program at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) and Wits Donald Gordon Medical Centre (WDGMC) from 2004 to 2017. We collected the following data per site: number of recipients, transplants performed, mean follow‐up time, and grafts lost; per recipient: age at time of transplant, sex, self‐reported population group; transplant history; donor type; etiology of ESKD; recipient and graft survival. Outcomes for era 1 were based on data published on our kidney transplant program, based at CMJAH. Results At CMJAH (public sector), there was no improvement in recipient and graft survival over time. In the contemporary analysis, 1‐, 5‐, and 10‐year recipient survival, as % (95% CI) was 93 (84‐97); 76 (64‐84); 59 (44‐70) for CMJAH, and 98 (90‐99); 95 (86‐99); 82 (54‐94) for WDGMC (private sector). Similarly, 1‐, 5‐ and 10‐year graft survival was 75 (63‐84); 55 (42‐66); 36 (24‐49) for CMJAH, and 96 (87‐99); 84 (73‐91); 64 (48‐76) at WDGMC. Conclusion Contemporary outcomes for the pediatric kidney transplant program at WDGMC are comparable to outcomes achieved in middle‐ and high‐income settings. However, outcomes at CMJAH are suboptimal, reflecting numerous health system, infrastructural and human resource challenges.

show abstract

Section: Introductionmentioning

confidence: 99%

Contemporary outcomes of the pediatric kidney transplant program in Johannesburg, South Africa, between 2004 and 2017: Better or not—And which way forward?

Mshumpela

Loveland

Botha

et al. 2020

Pediatric Transplantation

View full text Add to dashboard Cite

show abstract

“…Their efforts were successful.... the prototype strategy for induction of tolerance in large animals and in humans seemed at first to be obvious. (Starzl, 1993) 38 Het verschijnsel dat de Immunologisch actieve cellen in het getransplanteerde beenmerg een immuunreactie ontketenen op de (leukocyten)antigenen van de ontvanger. De 'eigen' cellen van de ontvanger worden door zijn 'niet eigen' immuunsysteem als vreemd gezien en dus aangevatlen.…”

Section: 'Rolls Royce Is Tot Volkswagen Cemaakt'unclassified

“…Within a few months, it became clear that GVHD similar to that in the perinatal mouse model could be expected almost invariably after all bone marrow engraftments that "took" following irradiation, except those from perfectly histocompatible donors. (Starzl. 1993) Al kan dit laatste toentertijd niet gezegd zijn.…”

Section: 'Rolls Royce Is Tot Volkswagen Cemaakt'mentioning

confidence: 99%

HLA & transplantatie : de ontwikkeling van een matchingspraktijk

Dorp¹

View full text Add to dashboard Cite

People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website.• The final author version and the galley proof are versions of the publication after peer review.• The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal.If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the "Taverne" license above, please follow below link for the End User Agreement:

show abstract

Schnittmengen und Pioniere

Larena‐Avellaneda

2018

Gefässchirurgie

View full text Add to dashboard Cite

The French heritage in clinical kidney transplantation

Cited by 7 publications

References 36 publications

Contemporary outcomes of the pediatric kidney transplant program in Johannesburg, South Africa, between 2004 and 2017: Better or not—And which way forward?

Contemporary outcomes of the pediatric kidney transplant program in Johannesburg, South Africa, between 2004 and 2017: Better or not—And which way forward?

HLA & transplantatie : de ontwikkeling van een matchingspraktijk

Schnittmengen und Pioniere

Contact Info

Product

Resources

About