In order to appraise the safety and reliability of bridges effectively, the comprehensive evaluation model based on analytic hierarchy process was established. The weight of evaluation index was calculated by using the model, and each evaluation index was given score by experts according to actual circumstances, and, on this basis, safety level of the bridge was obtained. And, afterwards, the model was applied to an engineering example for Huangjiaba Bridge. The results show that the evaluation level of bridge safety is third-level, with serious problems existing in this practical example, and the corresponding measures are proposed, which can provide scientific reference for bridge safety management.