The Formation and Development of Large Bodies in Proteus Vulgaris Ox-19 I

Demonstration of a Cell Wall in the Large Bodies of Proteus Vulgaris

“…Large body formation in P. vulgaris OX19 occurs in the same manner under the influence of penicillin as previously described under normal cultural conditions by Stempen and Hutchinson (1951). The lack of further development of the large bodies on nutrient agar containing penicillin is in agreement with reports on other strains of Proteus (Qrskov, 1947;Dienes, 1949;Tulasne, 1949a;Fleming et at., 1950;Pulvertaft, 1953;von Prittwitz and Gaffron, 1953) in which development into rods was obtained only when the spherical forms were transferred to media not containing penicillin.…”

The Reversion of the L Form of Proteus Mirabilis Into the Rod Form

“…However, the description (Dienes and Smith, 1944) deals with the development of large bodies which have formed from the bacilli not with the L forms found in the L type colonies. This process in Bacteroides is illustrated by photographs of living cells and is similar to that described by Stempen and Hutchinson (1951) for Proteus large bodies, but differs from the method described here for Proteus L forms.…”

“…The development of Proteus large bodies (as distinguished from L forms) into bacilli has been illustrated by time-lapse photography of living material by Stempen and Hutchinson (1951). The large body becomes irregular and divides into several bacteria, a process which is very different from the elongation and branching of the L forms.…”

The Formation and Development of Large Bodies in Proteus Vulgaris Ox-19 Ii

“…The appearance of diverse morphological forms in Proteus vulgaris OX-19 (Stempen and Hutchinson, 1951) stimulated interest in a cytological investigation of the organism to compare the chromatinic structures in the large bodies and other "atypical" forms with those in the "normal" rods. Cytological studies on large bodies of Proteus have been previously reported by Klieneberger-Nobel (1949), Tulasne (1949b), and Fleming et al (1950).…”