Flavor transitions via the charged current interactions are parametrized by a three dimensional and unitary transformation. This so called mixing matrix requires of four mixing parameters. Here we show that under the phenomenological observation of hierarchical fermion masses, m3 ≫ m2 ≫ m1, a mixing parametrization can be built with its mixing parameters being the corresponding four independent mass ratios of each fermion sector, i.e., mu/mc, mc/mt, m d /ms, and ms/m b and me/mµ, mµ/mτ , mν1/mν2, and mν2/mν3, for the quark and lepton sector, respectively.