Abstract:In chemotherapy, two or more pharmaceuticals targeting different metabolic pathways are often combined in the expectation that they will synergize or function additively against the tumor. Flavonoids, typically polycyclic plant pigments, have many beneficial effects in humans, including being putatively anticancer, inducing apoptosis by undefined means. Camptothecin (CPT), a powerful chemotherapeutic natural product used in Chinese traditional medicine is a topoisomerase inhibitor. In this study, we investigat… Show more
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