The first experience of the combined use of nitric oxide and molecular hydrogen for cardiac surgery in high-risk patients
V. V. Pichugin,
A. V. Deryugina,
S. E. Domnin
et al.
Abstract:The purpose of the study was to evaluate the effectiveness of myocardial protection with a combined supply of nitric oxide (NO) (40 ppm) and hydrogen (1.2 ppm) into the gas-air mixture delivery line of the cardiopulmonary bypass (CPB) machine during the entire period of CPB.Methods. The study included patients (n = 91) who had cardiac surgery under cardiopulmonary bypass and pharmacological cold cardioplegia. Patients were randomized into 3 groups. The Group 1 (n = 30) was control. Groups 2 (n = 28) and 3 (n =… Show more
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