<b><i>Introduction:</i></b> The <i>Kocuria</i> genus, encompassing gram-positive coccoid actinobacteria belonging to the Micrococcaceae family, has recently been discovered residing on the human skin and oral flora. Reports of <i>Kocuria</i>-associated infections in humans have been scarce. Herein, we present the first case of relapsing peritoneal dialysis (PD)-associated peritonitis caused by <i>Kocuria rhizophila</i>. <b><i>Case Presentation:</i></b> The patient, a 78-year-old male, presented with turbid effluent PD fluid, accompanied by an elevated white blood cell count of 253 cells/μL, of which 59% were neutrophils. A diagnosis of PD-associated peritonitis was established, leading to the initiation of intraperitoneal administration of ceftazidime and vancomycin. Subsequently, <i>Kocuria rhizophila</i> was identified through the bacterial culture of the dialysate. On the seventh day of initial treatment, the antibiotic regimen was changed to penicillin G, and the patient underwent a 3-week course of antibiotics. However, 1 week after discharge, the patient’s dialysis fluid became cloudy once again, with subsequent detection of <i>Kocuria rhizophila</i> in the fluid culture. Ultimately, the decision was made to remove the patient’s PD catheter and transition to hemodialysis. <b><i>Conclusion:</i></b> PD-associated peritonitis attributed to <i>Kocuria species</i> may be considered a potential risk for recurrence.