The First Case of L. pseudomesenteroides Pulmonary Infection and Literature Review

Dai, Liwan; Li, Yishi; Zhang, Xiaobing; Ding, Ming; Guo, Shuliang

doi:10.1155/2020/8818491

Cited by 2 publications

(4 citation statements)

References 20 publications

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“…Leuconostoc is intrinsically resistant to vancomycin (6). Clindamycin, linezolid, macrolides, aminoglycosides, cephalosporins, and tetracyclines have also been used to treat Leuconostoc infections, but the treatment of choice seems to be penicillin or ampicillin (4).…”

Section: Discussionmentioning

confidence: 99%

“…The mechanism of resistance seems to be chromosomally mediated and contrasts with the mechanism demonstrated by vancomycin-resistant enterococci. Because of its pentapeptide cell wall precursors ending in alanine-lactate rather than in the alanine-alanine dipeptide, which is the binding site for vancomycin in susceptible gram-positive cocci, Leuconostoc is intrinsically resistant to vancomycin (3,4). The microorganism was susceptible to ampicillin (≤8 µg/mL), penicillin (≤8 µg/mL), and chloramphenicol (≤8 µg/mL).…”

Section: Microbiological Identificationmentioning

confidence: 99%

“…The resistance mechanism appears to be chromosomally mediated and involves the production of peptidoglycan precursors ending in D-alanine-D-lactate, making these bacteria naturally resistant to glycopeptides. Leuconostoc species carry a gene that changes the D-ala-D-ala amino acid chain to D-ala-D-lactate, facilitating peptidoglycan wall formation and severely limiting vancomycin binding (3,4). A variety of infections have been reported among immunocompromised patients, though the first case of Leuconostoc infection was reported in 1985 (1,5).…”

Section: Introductionmentioning

confidence: 99%

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Atypical Presence of Leuconostoc pseudomesenteroides in a Lower Respiratory Tract Infection

Karnaker,

Ali Ashraf,

S Veetil

et al. 2024

Arch Clin Infect Dis

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Introduction: Leuconostoc species are gram-positive microorganisms typically isolated from dairy and brewing industries. Infections in humans are extremely rare. They are vaguely associated with patients who have co-morbidities and a history of antibiotic use. The rise of inadvertent microbiota complicates treatment delivery. Case Presentation: We report a rare case of Leuconostoc pseudomesenteroides in a patient with a lower respiratory tract infection. The patient suffered from diffuse axonal injury with bilateral subdural hematoma following a road traffic accident. An emergency tracheostomy was performed, and the patient was managed conservatively. The patient developed symptoms clinically, such as fever, and radiographically exhibited bilateral lung infiltrates. Endotracheal aspirate samples were sent for microbiological evaluation. Conclusions: The bacterial culture was identified as L. pseudomesenteroides. Bacterial identification and antibiotic susceptibility testing were verified. Antibiotics were administered empirically and intravenously until the patient achieved normal clinical status.

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Section: Discussionmentioning

confidence: 99%

Section: Microbiological Identificationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Atypical Presence of Leuconostoc pseudomesenteroides in a Lower Respiratory Tract Infection

Karnaker,

Ali Ashraf,

S Veetil

et al. 2024

Arch Clin Infect Dis

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“…from the blood of patients with malignant neoplasms and longterm catheterization, as well as from the removal of infected wounds, in postoperative infections and in odontogenic abscesses (4,12,(15)(16)(17). Pulmonary infection with Leuconostoc in a patient with lymphoma is also described (18). Xinfeng Lin and co-authors (19) in his paper associated hemophagocytic syndrome with Leuconostoc pseudomesenteroides infection in an adult patient.…”

Section: Introductionmentioning

confidence: 97%

Bacterium with Leuconostoc pseudomesenteroides

IAROVOI,

HOLBAN,

CHIRIACOV

et al. 2023

OH&RM

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Introduction. Leukonostoc pseudomesenteroides, widespread in nature (soil, plants, milk, etc.), until recently was classified as a commensal microorganism, but from 1985 until now several sporadic cases of infection with this pathogen have been described in humans. Bacteremia with Leuconostoc spp. are increasingly reported. Unique cases of infection of other sites have also been described: in soft, lung, urinary, Central Nervous System tissues, etc. Most often, these cases have been reported in patients with cancer, and are often considered opportunistic for acquired immunodeficiencies. However, several cases have also been reported in immunocompetent patients, including in those previously treated with vancomycin, Leuconostoc spp. having a natural resistance to this antibiotic. Material and methods. An analysis of the literature and the clinical case are presented here: the child of an 11-month-old with congenital malformation - rabbit lip, who underwent maxillofacial operation twice and had pneumonia 2 months before his admission to the Toma Ciorba Infectious Diseases Clinical Hospital. Results. Meningococcemia and meningitis were clinically established upon admission. The blood culture result was received a few days later, and Leuconostoc pseudomesenteroides was identified. The etiological treatment was corrected, after which the sterile result of the blood culture was obtained. The child was released in a satisfactory condition. Conclusions: The clinical case presented is the first case of infection with Leuconstoc spp. described in the Republic of Moldova. The correct choice of the etiological treatment allows the eradication of this pathogen, with a satisfactory clinical result.

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The First Case of L. pseudomesenteroides Pulmonary Infection and Literature Review

Cited by 2 publications

References 20 publications

Atypical Presence of Leuconostoc pseudomesenteroides in a Lower Respiratory Tract Infection

Atypical Presence of Leuconostoc pseudomesenteroides in a Lower Respiratory Tract Infection

Bacterium with Leuconostoc pseudomesenteroides

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